ID   GD25
AC   CVCL_7264
DR   Wikidata; Q54835527
RX   PubMed=7533171;
RX   PubMed=8567726;
RX   PubMed=10574722;
RX   PubMed=10601344;
CC   Knockout cell: Method=Gene trap; MGI; MGI:96610; Itgb1.
CC   Breed/subspecies: 129S2/SvPas.
OX   NCBI_TaxID=10090; ! Mus musculus
HI   CVCL_E078 ! G-201
SX   Male
AG   Blastocyst stage
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 13-11-18; Version: 10
RX   PubMed=7533171; DOI=10.1083/jcb.128.5.979;
RA   Fassler R., Pfaff M., Murphy J., Noegel A.A., Johansson S., Timpl R.,
RA   Albrecht R.;
RT   "Lack of beta 1 integrin gene in embryonic stem cells affects
RT   morphology, adhesion, and migration but not integration into the inner
RT   cell mass of blastocysts.";
RL   J. Cell Biol. 128:979-988(1995).
RX   PubMed=8567726; DOI=10.1083/jcb.132.1.227;
RA   Wennerberg K., Lohikangas L., Gullberg E.D., Pfaff M., Johansson S.,
RA   Fassler R.;
RT   "Beta 1 integrin-dependent and -independent polymerization of
RT   fibronectin.";
RL   J. Cell Biol. 132:227-238(1996).
RX   PubMed=10574722; DOI=10.1242/jcs.112.24.4751;
RA   Svineng G., Johansson S.;
RT   "Integrin subunits (beta)1C-1 and (beta)1C-2 expressed in GD25T cells
RT   are retained and degraded intracellularly rather than localised to the
RT   cell surface.";
RL   J. Cell Sci. 112:4751-4761(1999).
RX   PubMed=10601344; DOI=10.1083/jcb.147.6.1325;
RA   Gimond C., van der Flier A., van Delft S., Brakebusch C., Kuikman I.,
RA   Collard J.G., Fassler R., Sonnenberg A.;
RT   "Induction of cell scattering by expression of beta1 integrins in
RT   beta1-deficient epithelial cells requires activation of members of
RT   the rho family of GTPases and downregulation of cadherin and catenin
RT   function.";
RL   J. Cell Biol. 147:1325-1340(1999).