Home  |  Contact
Due to scheduled maintenance work, this service will not be available from Tuesday August 23rd 06:00 pm until Wednesday August 24th 08:00 am CEST. Apologies for the inconvenience.

Cellosaurus GM00638 (CVCL_7298)

[Text version]

Cell line name GM00638
Synonyms GM-638; GM0638; GM 638; GM638; GM00638A; GM54VA
Accession CVCL_7298
Resource Identification Initiative To cite this cell line use: GM00638 (RRID:CVCL_7298)
Comments Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from sampling site: Skin. Cell type=Fibroblast.
Sequence variations
  • Mutation; HGNC; 4135; GALT; Simple; p.Val44Met (c.130G>A); ClinVar=VCV000003611; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 4135; GALT; Simple; p.Met142Lys (c.425T>A); ClinVar=VCV000003609; Zygosity=Heterozygous (from parent cell line).
Disease Galactosemia (NCIt: C84723)
Galactosemia (ORDO: Orphanet_352)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_D342 (GM00054)
Sex of cell Male
Age at sampling 3M
Category Transformed cell line
Publications

DOI=10.5962/bhl.title.4090
Coriell L.L., Greene A.E.
The human genetic mutant cell repository: list of genetic variants, chromosomal aberrations and normal cell cultures submitted to the repository. 4th edition. October 1977.
(In) Institute for Medical Research (Camden, N.J.); pp.1-171; National Institutes of Health; Bethesda (1977)

PubMed=189310; DOI=10.1073/pnas.74.1.315
Croce C.M.
Assignment of the integration site for simian virus 40 to chromosome 17 in GM54VA, a human cell line transformed by simian virus 40.
Proc. Natl. Acad. Sci. U.S.A. 74:315-318(1977)

PubMed=191830; DOI=10.1073/pnas.74.3.1142
Koprowski H., Croce C.M.
Tumorigenicity of simian virus 40-transformed human cells and mouse-human hybrids in nude mice.
Proc. Natl. Acad. Sci. U.S.A. 74:1142-1146(1977)

PubMed=6256643; DOI=10.1038/288724a0
Day R.S. III, Ziolkowski C.H.J., Scudiero D.A., Meyer S.A., Lubiniecki A.S., Girardi A.J., Galloway S.M., Bynum G.D.
Defective repair of alkylated DNA by human tumour and SV40-transformed human cell strains.
Nature 288:724-727(1980)

PubMed=2463881; DOI=10.1093/carcin/10.2.265
Babich M.A., Day R.S. III
Synergistic killing of virus-transformed human cells with interferon and N-methyl-N'-nitro-N-nitrosoguanidine.
Carcinogenesis 10:265-268(1989)

PubMed=1766867; DOI=10.1093/nar/19.25.7049
Reichardt J.K.V.
Molecular analysis of 11 galactosemia patients.
Nucleic Acids Res. 19:7049-7052(1991)

CLPUB00447
Mulivor R.A., Suchy S.F.
1992/1993 catalog of cell lines. NIGMS human genetic mutant cell repository. 16th edition. October 1992.
(In) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda (1992)

PubMed=12361951; DOI=10.1074/jbc.M207937200
Donahue S.L., Campbell C.
A DNA double strand break repair defect in Fanconi anemia fibroblasts.
J. Biol. Chem. 277:46243-46247(2002)

Cross-references
Cell line collections Coriell; GM00638
Cell line databases/resources CLO; CLO_0003515
CLO; CLO_0028878
CLDB; cl1482
Encyclopedic resources Wikidata; Q54836364
Entry history
Entry creation04-Apr-2012
Last entry update17-Mar-2022
Version number21