Cellosaurus GTL-16 (CVCL_7668)

Cell line name GTL-16
Synonyms GTL 16; GTL16
Accession CVCL_7668
Resource Identification Initiative To cite this cell line use: GTL-16 (RRID:CVCL_7668)
Comments Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Gastric adenocarcinoma (NCIt: C4004)
Derived from metastatic site: Liver.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0434 (MKN45)
Children: CVCL_7696 (PR-GTL-16)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=2541345; DOI=10.1038/339155a0
Giordano S., Ponzetto C., Di Renzo M.F., Cooper C.S., Comoglio P.M.
Tyrosine kinase receptor indistinguishable from the c-met protein.
Nature 339:155-156(1989)

PubMed=1674365
Ponzetto C., Giordano S., Peverali F., Della Valle G., Abate M.L., Vaula G., Comoglio P.M.
c-met is amplified but not mutated in a cell line with an activated met tyrosine kinase.
Oncogene 6:553-559(1991)

PubMed=1486568; DOI=10.1016/0165-4608(92)90350-H
Rege-Cambrin G., Scaravaglio P., Carozzi F., Giordano S., Ponzetto C., Comoglio P.M., Saglio G.
Karyotypic analysis of gastric carcinoma cell lines carrying an amplified c-met oncogene.
Cancer Genet. Cytogenet. 64:170-173(1992)

PubMed=24807215; DOI=10.1038/ncomms4830
Liu J., McCleland M., Stawiski E.W., Gnad F., Mayba O., Haverty P.M., Durinck S., Chen Y.-J., Klijn C., Jhunjhunwala S., Lawrence M., Liu H., Wan Y., Chopra V., Yaylaoglu M.B., Yuan W., Ha C., Gilbert H.N., Reeder J., Pau G., Stinson J., Stern H.M., Manning G., Wu T.D., Neve R.M., de Sauvage F.J., Modrusan Z., Seshagiri S., Firestein R., Zhang Z.
Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer.
Nat. Commun. 5:3830-3830(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

Cross-references
Ontologies EFO; EFO_0006578
Chemistry resources ChEMBL-Cells; CHEMBL3308698
ChEMBL-Targets; CHEMBL612708
Gene expression databases GEO; GSM843505
GEO; GSM1374485
GEO; GSM1374486
Polymorphism and mutation databases Cosmic; 755306
Cosmic; 755613
Cosmic; 887246
Cosmic; 1945868
Cosmic; 2069777
Cosmic; 2484973