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Cellosaurus CEMR.3 (CVCL_7905)

[Text version]

Cell line name CEMR.3
Accession CVCL_7905
Resource Identification Initiative To cite this cell line use: CEMR.3 (RRID:CVCL_7905)
Comments Selected for resistance to: ChEBI; CHEBI:63486; 8-azaguanine.
Selected for resistance to: ChEBI; CHEBI:472805; Ouabain.
Derived from sampling site: Peripheral blood.
Sequence variations NKX2.5-BCL11B gene fusion (from parent cell line).
Heterozygous for FBXW7 p.Arg465Cys (c.1393C>T) (from parent cell line).
Heterozygous for FLT3 p.Ala627Thr (c.1879G>A) (from parent cell line).
Heterozygous for KRAS p.Gly12Asp (c.35G>A) (from parent cell line).
Heterozygous for NOTCH1 p.Leu1593_Arg1594insProArgLeuProHisAsnSerSerPheHisPheLeu (c.4780_4781ins36) and p.Pro2412Thr (c.7234C>A) (from parent cell line).
Heterozygous for TP53 p.Arg175His (c.524G>A) and p.Arg248Gln (c.743G>A) (from parent cell line).
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0207 (CCRF-CEM)
Children:
CVCL_7904 (T1)
Sex of cell Female
Age at sampling 3Y11M
Category Cancer cell line
Cross-references
Other Wikidata; Q54809289
Entry history
Entry creation04-Apr-2012
Last entry updated05-Jul-2019
Version number12