Home  |  Contact

Cellosaurus MOLM-14 (CVCL_7916)

[Text version]

Cell line name MOLM-14
Synonyms Molm-14; Molm 14; Molm14; MOLM14
Accession CVCL_7916
Resource Identification Initiative To cite this cell line use: MOLM-14 (RRID:CVCL_7916)
Comments Doubling time: 3-4 days (PubMed=9305600); ~50 hours (DSMZ).
Omics: Deep quantitative phosphoproteome analysis.
Omics: H3K79me1 ChIP-seq epigenome analysis.
Derived from sampling site: Peripheral blood.
Sequence variations KMT2A-MLLT3 (MLL-MLLT3; MLL-AF9) gene fusion (PubMed=9305600).
FLT3 internal tandem duplication (FLT3-ITD) (PubMed=12529668).
Disease Adult acute myeloid leukemia (NCIt: C9154)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_2119 ! MOLM-13
Sex of cell Male
Age at sampling 20Y
Category Cancer cell line
STR profile Source(s): COG; DSMZ

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133823,25
D3S135815
D5S81810,11
D7S82010,12
D8S117913,14
D13S31710,11
D16S53910,11
D18S5113,15
D19S43312,14
D21S1130,31
FGA21,23
TH017
TPOX8
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=9305600; DOI=10.1038/sj.leu.2400768
Matsuo Y., MacLeod R.A.F., Uphoff C.C., Drexler H.G., Nishizaki C., Katayama Y., Kimura G., Fujii N., Omoto E., Harada M., Orita K.
Two acute monocytic leukemia (AML-M5a) cell lines (MOLM-13 and MOLM-14) with interclonal phenotypic heterogeneity showing MLL-AF9 fusion resulting from an occult chromosome insertion, ins(11;9)(q23;p22p23).
Leukemia 11:1469-1477(1997)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=12529668; DOI=10.1038/sj.leu.2402740
Quentmeier H., Reinhardt J., Zaborski M., Drexler H.G.
FLT3 mutations in acute myeloid leukemia cell lines.
Leukemia 17:120-124(2003)

PubMed=21552520; DOI=10.1371/journal.pone.0019169
Gu T.-L., Nardone J., Wang Y., Loriaux M., Villen J., Beausoleil S., Tucker M., Kornhauser J., Ren J., MacNeill J., Gygi S.P., Druker B.J., Heinrich M.C., Rush J., Polakiewicz R.D.
Survey of activated FLT3 signaling in leukemia.
PLoS ONE 6:E19169-E19169(2011)

Cross-references
Cell line collections DSMZ; ACC-777
Cell line databases/resources Cell_Model_Passport; SIDM00436
Lonza; 978
Ontologies BTO; BTO:0005720
Chemistry resources ChEMBL-Cells; CHEMBL3706571
ChEMBL-Targets; CHEMBL3706570
Gene expression databases GEO; GSM2037134
GEO; GSM2037135
Other Wikidata; Q54906323
Polymorphism and mutation databases Cosmic; 787418
Cosmic; 1150898
Cosmic; 1281333
Entry history
Entry creation04-Apr-2012
Last entry updated05-Jul-2019
Version number15