Cellosaurus MOLM-14 (CVCL_7916)

Cell line name MOLM-14
Synonyms Molm-14; Molm 14; Molm14; MOLM14
Accession CVCL_7916
Resource Identification Initiative To cite this cell line use: MOLM-14 (RRID:CVCL_7916)
Comments Doubling time: 3-4 days (PubMed=9305600); ~50 hours (DSMZ).
Derived from sampling site: Peripheral blood.
Sequence variations FLT3 internal tandem duplication (FLT3-ITD) (PubMed=12529668).
Disease Adult acute myeloid leukemia (NCIt: C9154)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_2119 ! MOLM-13
Sex of cell Male
Age at sampling 20Y
Category Cancer cell line
STR profile Source(s): COG; DSMZ

Markers:
AmelogeninX,Y
CSF1PO10,12
D13S31710,11
D16S53910,11
D18S5113,15
D19S43312,14
D21S1130,31
D2S133823,25
D3S135815
D5S81810,11
D7S82010,12
D8S117913,14
FGA21,23
TH017
TPOX8
vWA16,17
Publications

DOI=10.1007/978-1-4757-1647-4_13
Biedler J.L.
Chromosome abnormalities in human tumor cells in culture.
(In) Human tumor cells in vitro; Fogh J. (eds.); pp.359-394; Springer; New York (1975)

PubMed=9305600; DOI=10.1038/sj.leu.2400768
Matsuo Y., MacLeod R.A.F., Uphoff C.C., Drexler H.G., Nishizaki C., Katayama Y., Kimura G., Fujii N., Omoto E., Harada M., Orita K.
Two acute monocytic leukemia (AML-M5a) cell lines (MOLM-13 and MOLM-14) with interclonal phenotypic heterogeneity showing MLL-AF9 fusion resulting from an occult chromosome insertion, ins(11;9)(q23;p22p23).
Leukemia 11:1469-1477(1997)

PubMed=12529668; DOI=10.1038/sj.leu.2402740
Quentmeier H., Reinhardt J., Zaborski M., Drexler H.G.
FLT3 mutations in acute myeloid leukemia cell lines.
Leukemia 17:120-124(2003)

Cross-references
Cell line collections DSMZ; ACC-777
Cell line databases/resources Lonza; 978
Ontologies BTO; BTO:0005720
Chemistry resources ChEMBL-Cells; CHEMBL3706571
ChEMBL-Targets; CHEMBL3706570
Other Wikidata; Q54906323
Polymorphism and mutation databases Cosmic; 787418
Cosmic; 1150898
Cosmic; 1281333