Cellosaurus MOLM-7 (CVCL_7917)

Cell line name MOLM-7
Synonyms MOLM7
Accession CVCL_7917
Resource Identification Initiative To cite this cell line use: MOLM-7 (RRID:CVCL_7917)
Comments Sequence variation: SMC3 p.Arg661Pro (PubMed=23955599).
Derived from sampling site: Peripheral blood.
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_2122 ! MOLM-6
CVCL_7918 ! MOLM-8
CVCL_7919 ! MOLM-9
CVCL_7920 ! MOLM-10
CVCL_7921 ! MOLM-11
CVCL_L075 ! MOLM-12
Sex of cell Male
Category Cancer cell line
Publications

PubMed=7873501
Tsuji-Takayama K., Kamiya T., Nakamura S., Matsuo Y., Adachi T., Tsubota T., Imanishi J., Minowada J.
Establishment of multiple leukemia cell lines with diverse myeloid and/or megakaryoblastoid characteristics from a single Ph1 positive chronic myelogenous leukemia blood sample.
Hum. Cell 7:167-171(1994)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

PubMed=23955599; DOI=10.1038/ng.2731
Kon A., Shih L.-Y., Minamino M., Sanada M., Shiraishi Y., Nagata Y., Yoshida K., Okuno Y., Bando M., Nakato R., Ishikawa S., Sato-Otsubo A., Nagae G., Nishimoto A., Haferlach C., Nowak D., Sato Y., Alpermann T., Nagasaki M., Shimamura T., Tanaka H., Chiba K., Yamamoto R., Yamaguchi T., Otsu M., Obara N., Sakata-Yanagimoto M., Nakamaki T., Ishiyama K., Nolte F., Hofmann W.K., Miyawaki S., Chiba S., Mori H., Nakauchi H., Koeffler H.P., Aburatani H., Haferlach T., Shirahige K., Miyano S., Ogawa S.
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
Nat. Genet. 45:1232-1237(2013)

Cross-references
Polymorphism and mutation databases Cosmic; 996325
Cosmic; 998757
Cosmic; 999770
Cosmic; 1012094
Cosmic; 1037677
Cosmic; 2089676