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Cellosaurus 253J-BV (CVCL_7937)

[Text version]

Cell line name 253J-BV
Synonyms 253JB-V; 253J B-V; 253JBV; 253J-Bladder-V
Accession CVCL_7937
Resource Identification Initiative To cite this cell line use: 253J-BV (RRID:CVCL_7937)
Comments Part of: BLA-40 bladder carcinoma cell line panel.
Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Population: Caucasian.
Characteristics: Metastatic phenotype. Obtained after 5 serial passages of the parent cell line in the bladder of nude mice.
Doubling time: 49 +- 5 hours (PubMed=7658585).
Microsatellite instability: Stable (MSS) (PubMed=31068700).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: Transcriptome analysis.
Disease Bladder carcinoma (NCIt: C4912)
Derived from metastatic site: Retroperitoneal lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7935 (253J)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
STR profile Source(s): KCLB


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PubMed=7658585; DOI=10.1016/S0022-5347(01)66923-4
Dinney C.P.N., Fishbeck R., Singh R.K., Eve B., Pathak S., Brown N., Xie B., Fan D., Bucana C.D., Fidler I.J., Killion J.J.
Isolation and characterization of metastatic variants from human transitional cell carcinoma passaged by orthotopic implantation in athymic nude mice.
J. Urol. 154:1532-1538(1995)

PubMed=29732388; DOI=10.3233/BLC-180167
Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cell line collections KCLB; 80002
Cell line databases/resources CCLE; 253JBV_URINARY_TRACT
Cell_Model_Passport; SIDM01624
DepMap; ACH-000026
Ontologies BTO; BTO:0004894
Biological sample resources BioSample; SAMN10987963
Chemistry resources PharmacoDB; 253JBV_15_2019
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM136239
Other Wikidata; Q54583655
Polymorphism and mutation databases Cosmic; 846282
Cosmic; 1082645
Cosmic; 1938695
IARC_TP53; 30015
LiGeA; CCLE_144
Entry history
Entry creation04-Apr-2012
Last entry update12-Jan-2021
Version number19