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Cellosaurus HAK-1B (CVCL_7958)

[Text version]

Cell line name HAK-1B
Accession CVCL_7958
Resource Identification Initiative To cite this cell line use: HAK-1B (RRID:CVCL_7958)
Comments Doubling time: 11 hours, at 19th passage (PubMed=8393423).
Sequence variations TP53 p.Cys242Tyr (c.725G>A) (ClinVar=VCV000012354) (PubMed=8393423).
HLA typing Source: PubMed=9178645
Class I
Class II
Disease Hepatitis C infection (NCIt: C3098)
Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_7957 ! HAK-1A
Sex of cell Male
Age at sampling 55Y
Category Cancer cell line

PubMed=8393423; DOI=10.1002/hep.1840180216
Yano H., Iemura A., Fukuda K., Mizoguchi A., Haramaki M., Kojiro M.
Establishment of two distinct human hepatocellular carcinoma cell lines from a single nodule showing clonal dedifferentiation of cancer cells.
Hepatology 18:320-327(1993)

PubMed=7537711; DOI=10.1002/hep.1840210510
Haramaki M., Yano H., Fukuda K., Momosaki S., Ogasawara S., Kojiro M.
Expression of CD44 in human hepatocellular carcinoma cell lines.
Hepatology 21:1276-1284(1995)

PubMed=9023415; DOI=10.1006/cimm.1996.1062
Seki N., Hoshino T., Kikuchi M., Hayashi A., Itoh K.
HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.
Cell. Immunol. 175:101-110(1997)

PubMed=9178645; DOI=10.1006/cimm.1997.1108
Nakao M., Sata M., Saitsu H., Yutani S., Kawamoto M., Kojiro M., Itoh K.
CD4+ hepatic cancer-specific cytotoxic T lymphocytes in patients with hepatocellular carcinoma.
Cell. Immunol. 177:176-181(1997)

PubMed=10347112; DOI=10.1002/hep.510290624
Yano H., Iemura A., Haramaki M., Ogasawara S., Takayama A., Akiba J., Kojiro M.
Interferon alfa receptor expression and growth inhibition by interferon alfa in human liver cancer cell lines.
Hepatology 29:1708-1717(1999)

PubMed=27329724; DOI=10.18632/oncotarget.10161
Watari K., Nishitani A., Shibata T., Noda M., Kawahara A., Akiba J., Murakami Y., Yano H., Kuwano M., Ono M.
Phosphorylation of mTOR Ser2481 is a key target limiting the efficacy of rapalogs for treating hepatocellular carcinoma.
Oncotarget 7:47403-47417(2016)

Other Wikidata; Q54872379
Entry history
Entry creation04-Apr-2012
Last entry update02-Jul-2020
Version number13