Cellosaurus HPB-MLT (CVCL_7959)

Cell line name HPB-MLT
Synonyms FCCH1019
Accession CVCL_7959
Resource Identification Initiative To cite this cell line use: HPB-MLT (RRID:CVCL_7959)
Comments Problematic cell line: Contaminated. Shown to be a HPB-ALL derivative (PubMed=12592342, PubMed=20143388).
Sequence variation: TP53 p.Cys124Ter (from parent cell line).
Misspelling: MPB-MLT; In PubMed=10071127.
Derived from sampling site: Peripheral blood.
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1820 (HPB-ALL)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): TKG

Markers:
AmelogeninX,Y
CSF1PO10,11
D13S3178,10
D16S5399,11
D5S81811
D7S82011
TH017,9
TPOX8,12
vWA18,20
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations-v8_0.pdf
Publications

PubMed=203546; DOI=10.1002/ijc.2910210207
Morikawa S., Tatsumi E., Baba M., Harada T., Yasuhira K.
Two E-rosette-forming lymphoid cell lines.
Int. J. Cancer 21:166-170(1978)

PubMed=1373528
Duan D.-S., Smith W., Sadee W., Cowan M.J.
Characterization of three T-lymphoid cell lines with distinct sensitivities to deoxyadenosine plus deoxycoformycin.
Thymus 19:1-11(1992)

PubMed=10071127; DOI=10.1016/S0145-2126(98)00146-5
Kawamura M., Ohnishi H., Guo S.X., Sheng X.M., Minegishi M., Hanada R., Horibe K., Hongo T., Kaneko Y., Bessho F., Yanagisawa M., Sekiya T., Hayashi Y.
Alterations of the p53, p21, p16, p15 and RAS genes in childhood T-cell acute lymphoblastic leukemia.
Leuk. Res. 23:115-126(1999)

PubMed=12592342; DOI=10.1038/sj.leu.2402799
Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F.
False leukemia-lymphoma cell lines: an update on over 500 cell lines.
Leukemia 17:416-426(2003)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line collections TKG; TKG 0361
Biological sample resources BioSample; SAMN03151780
Polymorphism and mutation databases Cosmic; 721703
Cosmic; 801733
Cosmic; 998731