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Cellosaurus TTC-549 (CVCL_8005)

Cell line name TTC-549
Synonyms TTC549
Accession CVCL_8005
Resource Identification Initiative To cite this cell line use: TTC-549 (RRID:CVCL_8005)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: ENCODE project common cell types; tier 3.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
Disease Extrarenal rhabdoid tumor (NCIt: C6586)
Rhabdoid tumor (ORDO: Orphanet_69077)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 6M
Category Cancer cell line
Web pages http://genome.ucsc.edu/ENCODE/protocols/cell/human/MRTTTC549_Crawford_protocol.pdf
Publications

PubMed=8818656; DOI=10.1002/(SICI)1098-2264(199606)16:2<94::AID-GCC3>3.0.CO;2-Y
Biegel J.A., Allen C.S., Kawasaki K., Shimizu N., Budarf M.L., Bell C.J.
Narrowing the critical region for a rhabdoid tumor locus in 22q11.
Genes Chromosomes Cancer 16:94-105(1996)

PubMed=9559292; DOI=10.1097/00019606-199712000-00004
Suzuki A., Ohta S., Shimada M.
Gene expression of malignant rhabdoid tumor cell lines by reverse transcriptase-polymerase chain reaction.
Diagn. Mol. Pathol. 6:326-332(1997)

PubMed=9920784; DOI=10.1006/bbrc.1998.9968
Mori T., Fukuda Y., Kuroda H., Matsumura T., Ota S., Sugimoto T., Nakamura Y., Inazawa J.
Cloning and characterization of a novel Rab-family gene, Rab36, within the region at 22q11.2 that is homozygously deleted in malignant rhabdoid tumors.
Biochem. Biophys. Res. Commun. 254:594-600(1999)

PubMed=10602515; DOI=10.1038/sj.onc.1203168
DeCristofaro M.F., Betz B.L., Wang W.-D., Weissman B.E.
Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors.
Oncogene 18:7559-7565(1999)

PubMed=11557780; DOI=10.1038/modpathol.3880401
Itakura E., Tamiya S., Morita K., Shiratsuchi H., Kinoshita Y., Oshiro Y., Oda Y., Ohta S., Furue M., Tsuneyoshi M.
Subcellular distribution of cytokeratin and vimentin in malignant rhabdoid tumor: three-dimensional imaging with confocal laser scanning microscopy and double immunofluorescence.
Mod. Pathol. 14:854-861(2001)

PubMed=11921280; DOI=10.1002/gcc.10052
Uno K., Takita J., Yokomori K., Tanaka Y., Ohta S., Shimada H., Gilles F.H., Sugita K., Abe S., Sako M., Hashizume K., Hayashi Y.
Aberrations of the hSNF5/INI1 gene are restricted to malignant rhabdoid tumors or atypical teratoid/rhabdoid tumors in pediatric solid tumors.
Genes Chromosomes Cancer 34:33-41(2002)

PubMed=12210830; DOI=10.1002/jnr.10330
Yoshida S., Narita T., Taga T., Ohta S., Takeuchi Y.
Malignant rhabdoid tumor shows incomplete neural characteristics as revealed by expression of SNARE complex.
J. Neurosci. Res. 69:642-652(2002)

PubMed=16557275; DOI=10.1038/modpathol.3800599
Izumi T., Oda Y., Hasegawa T., Nakanishi Y., Iwasaki H., Sonobe H., Goto H., Kusakabe H., Takahira T., Kobayashi C., Kawaguchi K.-i., Saito T., Yamamoto H., Tamiya S., Iwamoto Y., Tsuneyoshi M.
Prognostic significance of dysadherin expression in epithelioid sarcoma and its diagnostic utility in distinguishing epithelioid sarcoma from malignant rhabdoid tumor.
Mod. Pathol. 19:820-831(2006)

PubMed=24418192; DOI=10.1111/cas.12352
Takita J., Chen Y.-Y., Kato M., Ohki K., Sato Y., Ohta S., Sugita K., Nishimura R., Hoshino N., Seki M., Sanada M., Oka A., Hayashi Y., Ogawa S.
Genome-wide approach to identify second gene targets for malignant rhabdoid tumors using high-density oligonucleotide microarrays.
Cancer Sci. 105:258-264(2014)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line databases/resources Cell_Model_Passport; SIDM01457
DepMap; ACH-001211
Biological sample resources BioSample; SAMN10989627
ENCODE; ENCBS258AAA
Encyclopedic resources Wikidata; Q54973250
Experimental variables resources EFO; EFO_0005700
Gene expression databases GEO; GSM3145740
Polymorphism and mutation databases Cosmic; 801776
Cosmic; 802052
Cosmic; 1063888
Cosmic; 2144784
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number24