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Cellosaurus TTC-709 (CVCL_8007)

Cell line name TTC-709
Synonyms TTC709
Accession CVCL_8007
Resource Identification Initiative To cite this cell line use: TTC-709 (RRID:CVCL_8007)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Omics: Deep exome analysis.
Sequence variations
  • Gene deletion; HGNC; 11103; SMARCB1; Zygosity=Homozygous (PubMed=10602515).
Disease Extrarenal rhabdoid tumor (NCIt: C6586)
Rhabdoid tumor (ORDO: Orphanet_69077)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
STR profile Source(s): DepMap

Markers:
AmelogeninX,Y
CSF1PO10,12
D3S135815,16
D5S81810,11
D7S82011
D8S117910,15
D13S3179,12
D16S53911,13
D18S5112,17
D21S1129,30
FGA22,26
Penta D10,17
Penta E5,16
TH017
TPOX8,11
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=10602515; DOI=10.1038/sj.onc.1203168
DeCristofaro M.F., Betz B.L., Wang W.-D., Weissman B.E.
Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors.
Oncogene 18:7559-7565(1999)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line databases/resources Cell_Model_Passport; SIDM01455
DepMap; ACH-000597
Biological sample resources BioSample; SAMN10989625
Chemistry resources PharmacoDB; TTC709_1608_2019
Encyclopedic resources Wikidata; Q54973253
Gene expression databases GEO; GSM3145742
Polymorphism and mutation databases Cosmic; 802054
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number15