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Cellosaurus T3M-10 (CVCL_8067)

[Text version]

Cell line name T3M-10
Synonyms T3M10
Accession CVCL_8067
Resource Identification Initiative To cite this cell line use: T3M-10 (RRID:CVCL_8067)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: NCI RAS program mutant KRAS cell line panel.
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Sequence variations Heterozygous for KRAS p.Gly12Asp (c.35G>A) (CCLE).
Homozygous for TP53 p.Ala161Thr (c.481G>A) (CCLE).
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.75
Native American0
East Asian, North84.13
East Asian, South11.41
South Asian0
European, North0
European, South2.71
Disease Large cell lung carcinoma (NCIt: C4450)
Derived from metastatic site: Lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 40Y
Category Cancer cell line
STR profile Source(s): RCB

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S81811
D7S82011,14
D13S31711
D16S5399,10
TH016,9
TPOX8
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=6088016; DOI=10.1002/1097-0142(19840915)54:6<1024::AID-CNCR2820540616>3.0.CO;2-1
Okabe T., Fujisawa M., Kudo H., Honma H., Ohsawa N., Takaku F.
Establishment of a human colony-stimulating-factor-producing cell line from an undifferentiated large cell carcinoma of the lung.
Cancer 54:1024-1029(1984)

PubMed=6091874
Okabe T., Kaizu T., Fujisawa M., Watanabe J., Kojima K., Yamashita T., Takaku F.
Monoclonal antibodies to surface antigens of small cell carcinoma of the lung.
Cancer Res. 44:5273-5278(1984)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections RCB; RCB1020
Cell line databases/resources CCLE; T3M10_LUNG
DepMap; ACH-000813
Ontologies CLO; CLO_0050071
Biological sample resources BioSample; SAMN03472206
BioSample; SAMN10988110
Chemistry resources PharmacoDB; T3M10_1556_2019
Gene expression databases ArrayExpress; E-MTAB-2770
Other Wikidata; Q54971532
Polymorphism and mutation databases IARC_TP53; 28362
LiGeA; CCLE_753
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number15