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Cellosaurus A-2182 (CVCL_8091)

[Text version]

Cell line name A-2182
Synonyms A2182
Accession CVCL_8091
Resource Identification Initiative To cite this cell line use: A-2182 (RRID:CVCL_8091)
Comments From: Aaronson S.A.; Mt. Sinai Medical Center; New York; USA.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Arg (c.34G>C); ClinVar=VCV000012579; Zygosity=Unspecified (PubMed=1855224).
Disease Lung squamous cell carcinoma (NCIt: C3493)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line

PubMed=7144906; DOI=10.1038/300539a0
Pulciani S., Santos E., Lauver A.V., Long L.K., Aaronson S.A., Barbacid M.
Oncogenes in solid human tumours.
Nature 300:539-542(1982)

PubMed=6825208; DOI=10.1093/carcin/4.2.199
Yarosh D.B., Foote R.S., Mitra S., Day R.S. III
Repair of O6-methylguanine in DNA by demethylation is lacking in Mer- human tumor cell strains.
Carcinogenesis 4:199-205(1983)

PubMed=3413074; DOI=10.1073/pnas.85.16.6042
Pereira-Smith O.M., Smith J.R.
Genetic analysis of indefinite division in human cells: identification of four complementation groups.
Proc. Natl. Acad. Sci. U.S.A. 85:6042-6046(1988)

Lehman T.A., Bennett W.P., Metcalf R.A., Welsh J.A., Ecker J., Modali R.V., Ullrich S., Romano J.W., Appella E., Testa J.R., Gerwin B.I., Harris C.C.
p53 mutations, ras mutations, and p53-heat shock 70 protein complexes in human lung carcinoma cell lines.
Cancer Res. 51:4090-4096(1991)

PubMed=15848055; DOI=10.1016/j.ejpb.2004.12.002
Rengel R.G., Filipovic-Grcic J., Cepelak I., Zanic-Grubisic T., Barisic K.
The effect of liposomes with superoxide dismutase on A2182 cells.
Eur. J. Pharm. Biopharm. 60:47-51(2005)

Encyclopedic resources Wikidata; Q54606447
Polymorphism and mutation databases Cosmic; 929963
Cosmic; 932916
Cosmic; 2668260
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number9