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Cellosaurus A-2182 (CVCL_8091)

[Text version]
Cell line name A-2182
Synonyms A2182
Accession CVCL_8091
Resource Identification Initiative To cite this cell line use: A-2182 (RRID:CVCL_8091)
Comments From: Aaronson S.A.; Mt. Sinai Medical Center; New York; USA.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Arg (c.34G>C); ClinVar=VCV000012579; Zygosity=Unspecified (PubMed=1855224).
Disease Lung squamous cell carcinoma (NCIt: C3493)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=7144906; DOI=10.1038/300539a0
Pulciani S., Santos E., Lauver A.V., Long L.K., Aaronson S.A., Barbacid M.
Oncogenes in solid human tumours.
Nature 300:539-542(1982)

PubMed=6825208; DOI=10.1093/carcin/4.2.199
Yarosh D.B., Foote R.S., Mitra S., Day R.S. III
Repair of O6-methylguanine in DNA by demethylation is lacking in Mer- human tumor cell strains.
Carcinogenesis 4:199-205(1983)

PubMed=3413074; DOI=10.1073/pnas.85.16.6042
Pereira-Smith O.M., Smith J.R.
Genetic analysis of indefinite division in human cells: identification of four complementation groups.
Proc. Natl. Acad. Sci. U.S.A. 85:6042-6046(1988)

PubMed=1855224
Lehman T.A., Bennett W.P., Metcalf R.A., Welsh J.A., Ecker J., Modali R.V., Ullrich S., Romano J.W., Appella E., Testa J.R., Gerwin B.I., Harris C.C.
p53 mutations, ras mutations, and p53-heat shock 70 protein complexes in human lung carcinoma cell lines.
Cancer Res. 51:4090-4096(1991)

PubMed=15848055; DOI=10.1016/j.ejpb.2004.12.002
Rengel R.G., Filipovic-Grcic J., Cepelak I., Zanic-Grubisic T., Barisic K.
The effect of liposomes with superoxide dismutase on A2182 cells.
Eur. J. Pharm. Biopharm. 60:47-51(2005)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8091
Encyclopedic resources Wikidata; Q54606447
Polymorphism and mutation databases Cosmic; 929963
Cosmic; 932916
Cosmic; 2668260
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number11