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Cellosaurus FL-318 (CVCL_8095)

[Text version]

Cell line name FL-318
Synonyms FL318
Accession CVCL_8095
Resource Identification Initiative To cite this cell line use: FL-318 (RRID:CVCL_8095)
Comments Doubling time: 45.2 hours (PubMed=8847894).
Omics: Array-based CGH.
Omics: CNV analysis.
Omics: miRNA expression profiling.
Omics: Transcriptome analysis.
Misspelling: AKA96-9; In IARC TP53 database: not really a misspelling but an assignment of a name based on first author of publication and date because assignment of correct cell line name was not done correctly.
Derived from sampling site: Ascites.
Sequence variations TP53 p.Val274Leu (c.820G>C) (PubMed=8878455).
Disease Follicular lymphoma (NCIt: C3209)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 67Y
Category Cancer cell line
Publications

PubMed=2180570
Amakawa R., Fukuhara S., Ohno H., Tanabe S., Horii M., Matsuyama F., Kato I., Kakita T., Nagauchi O.
Amplified and rearranged bcl-2 gene in two lymphoma cell lines, FL-218 and FL-318, carrying a 14;18 translocation.
Cancer Res. 50:2423-2428(1990)

PubMed=8847894
Tani A., Tatsumi E., Nakamura F., Kumagai S., Kosaka Y., Sano K., Nakamura H., Amakawa R., Ohno H.
Sensitivity to dexamethasone and absence of bcl-2 protein in Burkitt's lymphoma cell line (Black93) derived from a patient with acute tumor lysis syndrome: comparative study with other BL and non-BL lines.
Leukemia 10:1592-1603(1996)

PubMed=8878455; DOI=10.1111/j.1349-7006.1996.tb02122.x
Akasaka T., Muramatsu M., Kadowaki N., Ohno H., Ishizaki K., Yamabe H., Fukuhara S., Okuma M.
p53 mutation in B-cell lymphoid neoplasms with reference to oncogene rearrangements associated with chromosomal translocations.
Jpn. J. Cancer Res. 87:930-937(1996)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=12967475; DOI=10.1111/j.1349-7006.2003.tb01518.x
Maesako Y., Uchiyama T., Ohno H.
Comparison of gene expression profiles of lymphoma cell lines from transformed follicular lymphoma, Burkitt's lymphoma and de novo diffuse large B-cell lymphoma.
Cancer Sci. 94:774-781(2003)

PubMed=14990977; DOI=10.1038/sj.leu.2403323
Hardianti M.S., Tatsumi E., Syampurnawati M., Furuta K., Saigo K., Nakamachi Y., Kumagai S., Ohno H., Tanabe S., Uchida M., Yasuda N.
Activation-induced cytidine deaminase expression in follicular lymphoma: association between AID expression and ongoing mutation in FL.
Leukemia 18:826-831(2004)

PubMed=19278952; DOI=10.1182/blood-2009-01-202028
Li C., Kim S.-W., Rai D., Bolla A.R., Adhvaryu S., Kinney M.C., Robetorye R.S., Aguiar R.C.T.
Copy number abnormalities, MYC activity, and the genetic fingerprint of normal B cells mechanistically define the microRNA profile of diffuse large B-cell lymphoma.
Blood 113:6681-6690(2009)

Cross-references
Ontologies BTO; BTO:0002520
Gene expression databases GEO; GSM380126
Other Wikidata; Q54834955
Polymorphism and mutation databases IARC_TP53; 6005
Entry history
Entry creation04-Apr-2012
Last entry updated25-Feb-2019
Version number11