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Cellosaurus JH-EsoAd1 (CVCL_8098)

[Text version]

Cell line name JH-EsoAd1
Synonyms JHEsoAD1; JHesoAD1; JHESOAD1
Accession CVCL_8098
Resource Identification Initiative To cite this cell line use: JH-EsoAd1 (RRID:CVCL_8098)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: 20 hours (PubMed=18787394); 29 hours (PubMed=25984343).
Omics: Deep exome analysis.
Omics: Genome sequenced.
Omics: shRNA library screening.
Sequence variations Homozygous for TP53 p.Gly266Glu (c.797G>A) (PubMed=18787394; PubMed=20075370; CCLE).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.64
Native American0
East Asian, North1.94
East Asian, South0
South Asian0
European, North58.42
European, South38.99
Disease Barrett adenocarcinoma (NCIt: C7027)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): PubMed=18787394; PubMed=20075370

Markers:
AmelogeninX
CSF1PO10
D3S135816
D5S81811
D7S82010,12
D8S117910
D13S31711
D16S53910,12
D18S5112
D21S1130
FGA24
Penta D14
Penta E11
TH016,7
TPOX8,9
vWA19 (PubMed=18787394)
18,19 (PubMed=20075370)

Run an STR similarity search on this cell line
Publications

PubMed=18787394; DOI=10.4161/cbt.7.11.6723
Alvarez H., Koorstra J.B., Hong S.M., Boonstra J.J., Dinjens W.N.M., Foratiere A.A., Wu T.T., Montgomery E., Eshleman J.R., Maitra A.
Establishment and characterization of a bona fide Barrett esophagus-associated adenocarcinoma cell line.
Cancer Biol. Ther. 7:1753-1755(2008)

PubMed=20075370; DOI=10.1093/jnci/djp499
Boonstra J.J., van Marion R., Beer D.G., Lin L., Chaves P., Ribeiro C., Pereira A.D., Roque L., Darnton S.J., Altorki N.K., Schrump D.S., Klimstra D.S., Tang L.H., Eshleman J.R., Alvarez H., Shimada Y., van Dekken H., Tilanus H.W., Dinjens W.N.M.
Verification and unmasking of widely used human esophageal adenocarcinoma cell lines.
J. Natl. Cancer Inst. 102:271-274(2010)

PubMed=25984343; DOI=10.1038/sdata.2014.35
Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S., East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H., Jiang G., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M., Harrington W., Gelfand E., Green T.M., Tomko M.J., Gopal S., Wong T.C., Li H., Howell S., Stransky N., Liefeld T., Jang D., Bistline J., Hill Meyers B., Armstrong S.A., Anderson K.C., Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P., Golub T.R., Root D.E., Hahn W.C.
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Sci. Data 1:140035-140035(2014)

PubMed=23795680; DOI=10.1111/dote.12095
Boonstra J.J., Tilanus H.W., Dinjens W.N.M.
Translational research on esophageal adenocarcinoma: from cell line to clinic.
Dis. Esophagus 28:90-96(2015)

DOI=10.12688/f1000research.7033.1
Contino G., Eldridge M.D., Secrier M., Bower L., Elliott R.F., Weaver J., Lynch A.G., Edwards P.A.W., Fitzgerald R.C.
Whole-genome sequencing of nine esophageal adenocarcinoma cell lines.
F1000Research 5:1336-1336(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line databases/resources CCLE; JHESOAD1_OESOPHAGUS
DepMap; ACH-000216
Biological sample resources BioSample; SAMN10988422
Other Wikidata; Q54898624
Polymorphism and mutation databases Cosmic; 1599340
Entry history
Entry creation04-Apr-2012
Last entry updated05-Jul-2019
Version number12