Cell line name |
HMy.2 B |
Synonyms |
LICR-Lon-HMy-2; LICR-LON-HMy2; LICR.LON.HMy2; Licr.Lon.Hmy2; LICRLON/My2; Hmy2; LICR-2 |
Accession |
CVCL_8119 |
Resource Identification Initiative |
To cite this cell line use: HMy.2 B (RRID:CVCL_8119) |
Comments |
Group: Hybridoma fusion partner cell line. Population: Caucasian. Doubling time: 24 hours (Patent=US4695538). Selected for resistance to: ChEBI; CHEBI:63486; 8-azaguanine. Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: B-cell; CL=CL_0000236. |
HLA typing |
Source: IPD-IMGT/HLA=10744
Class I | HLA-A | A*02:01 | HLA-B | B*35:03 | HLA-C | C*04:01 |
Source: CLS=302008
Class I | HLA-A | A*02:01:01,03:01:01 | HLA-B | B*15:01:01,35:03:01 | HLA-C | C*03:04:01,04:01:01 | Class II | HLA-DP | DPB1*03:01:01,04:01:01 | HLA-DQ | DQA1*03:01:01,05:05:01 | | DQB1*03:01:01,03:02:01 | HLA-DR | DRB1*04:01:01,12:01:01 |
|
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_1072 (ARH-77) Children:
|
Sex of cell |
Female |
Age at sampling |
33Y |
Category |
Transformed cell line |
STR profile |
Source(s): CLS; TKG
Markers:Amelogenin | X |
CSF1PO | 6,10 |
D2S1338 | 17 |
D3S1358 | 16 |
D5S818 | 10,13 |
D7S820 | 7,12 |
D8S1179 | 14,15 |
D13S317 | 11,13 |
D16S539 | 9,13 (TKG) 13 (CLS) |
D18S51 | 4,16 |
D19S433 | 14,15 |
D21S11 | 29,30 |
FGA | 20,21 |
TH01 | 8,9.3 |
TPOX | 8 |
vWA | 17 |
Run an STR similarity search on this cell line |
Publications | PubMed=7140810; DOI=10.1002/eji.1830120804 Edwards P.A.W., Smith C.M., Neville A.M., O'Hare M.J. A human-hybridoma system based on a fast-growing mutant of the ARH-77 plasma cell leukemia-derived line. Eur. J. Immunol. 12:641-648(1982) PubMed=6350451; DOI=10.4049/jimmunol.131.3.1201 Abrams P.G., Knost J.A., Clarke G., Wilburn S., Oldham R.K., Foon K.A. Determination of the optimal human cell lines for development of human hybridomas. J. Immunol. 131:1201-1204(1983) PubMed=6864164; DOI=10.1084/jem.158.1.53 Houghton A.N., Brooks H., Cote R.J., Taormina M.C., Oettgen H.F., Old L.J. Detection of cell surface and intracellular antigens by human monoclonal antibodies. Hybrid cell lines derived from lymphocytes of patients with malignant melanoma. J. Exp. Med. 158:53-65(1983) DOI=10.1007/978-1-4613-2823-0_29 Karpas A. Viruses and human leukemia in vitro. (In) Human leukemia. Cytochemical and ultrastructural techniques in diagnosis and research. Developments in Oncology, Vol. 14; Polliack A. (eds.); pp.495-526; Martinus Nijhoff Publishing; Boston (1984) PubMed=6582512; DOI=10.1073/pnas.81.2.568 Mattes M.J., Cordon-Cardo C., Lewis J.L. Jr., Old L.J., Lloyd K.O. Cell surface antigens of human ovarian and endometrial carcinoma defined by mouse monoclonal antibodies. Proc. Natl. Acad. Sci. U.S.A. 81:568-572(1984) Patent=US4695538 Cote R.J., Thomson T.M., Houghton A.N., Oettgen H.F., Old L.J., Cardo C.C. Human monoclonal antibodies to cell surface antigens. Patent number US4695538, 22-Sep-1987 |
Cross-references |
Cell line collections (Providers) |
CLS; 302008
TKG; TKG 0221
|
Cell line databases/resources |
IPD-IMGT/HLA; 10744
|
Encyclopedic resources |
Wikidata; Q54889980
|
Entry history |
Entry creation | 04-Apr-2012 |
Last entry update | 05-Oct-2023 |
Version number | 21 |
---|