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Cellosaurus L3.4 (CVCL_8146)

[Text version]
Cell line name L3.4
Accession CVCL_8146
Resource Identification Initiative To cite this cell line use: L3.4 (RRID:CVCL_8146)
Comments Population: African American.
Derived from site: Metastatic; Celiac axis lymph node; UBERON=UBERON_0002508.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (from parent cell line).
Disease Pancreatic adenosquamous carcinoma (NCIt: C5721)
Squamous cell carcinoma of pancreas (ORDO: Orphanet_424039)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_8147 (L3.3)
Children:
CVCL_8145 (L3.5)
Sex of cell Female
Age at sampling 77Y
Category Cancer cell line
Publications

PubMed=1544114; DOI=10.1002/1097-0142(19920415)69:8<2060::AID-CNCR2820690810>3.0.CO;2-E
Vezeridis M.P., Tzanakakis G.N., Meitner P.A., Doremus C.M., Tibbetts L.M., Calabresi P.
In vivo selection of a highly metastatic cell line from a human pancreatic carcinoma in the nude mouse.
Cancer 69:2060-2063(1992)

PubMed=15235133; DOI=10.1385/IJGC:34:1:27
Tzanakakis G.N., Margioris A.N., Tsatsakis A.M., Vezeridis M.P.
The metastatic potential of human pancreatic cell lines in the liver of nude mice correlates well with cathepsin B activity.
Int. J. Gastrointest. Cancer 34:27-38(2003)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8146
Encyclopedic resources Wikidata; Q54901021
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number18