Cell line name | MOLT-15 |
---|---|
Synonyms | Molt-15; MOLT 15 |
Accession | CVCL_8150 |
Resource Identification Initiative | To cite this cell line use: MOLT-15 (RRID:CVCL_8150) |
Comments | Problematic cell line: Contaminated. Shown to be a CTV-1 derivative (PubMed=10508494; PubMed=12592342; PubMed=20143388). Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00147. Derived from sampling site: Peripheral blood. |
Sequence variations | Heterozygous for FBXW7 p.Gly477Ser (c.1429G>A) (from parent cell line).Heterozygous for FBXW7 p.Arg505Cys (c.1513C>T) (ClinVar=VCV000069961) (from parent cell line).Heterozygous for FLT3 p.Gly831Glu (c.2492G>A) (from parent cell line).Heterozygous for LCK p.Ala353Val (c.1058C>T) (from parent cell line).Heterozygous for LCK p.Pro447Leu (c.1340C>T) (from parent cell line).Heterozygous for LCK p.Ala500Thr (c.1498G>A) (from parent cell line).Heterozygous for NF1 p.Gly1532Arg (c.4594G>A) (from parent cell line).Heterozygous for NOTCH1 p.Ser2523Ter (c.7568C>A) (PubMed=15472075).Heterozygous for PDGFRB p.Met772Ile (c.2316G>A) (from parent cell line).Heterozygous for RET p.Cys656Phe (c.1967G>T) (from parent cell line).Heterozygous for STK11 p.Arg75Met (c.224G>T) (from parent cell line).Heterozygous for STK11 p.Lys175Met (c.524A>T) (from parent cell line). |
Disease | Adult T acute lymphoblastic leukemia (NCIt: C9142) Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) |
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
|
Hierarchy | Parent: CVCL_1150 (CTV-1) |
Sex of cell | Male |
Age at sampling | Age unspecified |
Category | Cancer cell line |
Web pages | http://iclac.org/wp-content/uploads/Cross-Contaminations_v10_distribution.xlsx |
Publications | PubMed=2784121; DOI=10.1002/hon.2900070203 PubMed=9933131; DOI=10.1016/S0145-2126(98)00133-7 PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2 PubMed=12592342; DOI=10.1038/sj.leu.2402799 PubMed=15472075; DOI=10.1126/science.1102160 PubMed=20143388; DOI=10.1002/ijc.25242 |
Cross-references | |
Biological sample resources | BioSample; SAMN03151632 |
Other | Wikidata; Q54906346 |
Polymorphism and mutation databases | Cosmic; 913415
Cosmic; 1524806 |
Entry history | |
Entry creation | 04-Apr-2012 |
Last entry update | 12-Jan-2021 |
Version number | 19 |