Cellosaurus Hu456 (CVCL_8238)

Cell line name Hu456
Synonyms Hu 456; HU 456; HU456
Accession CVCL_8238
Resource Identification Initiative To cite this cell line use: Hu456 (RRID:CVCL_8238)
Comments Problematic cell line: Contaminated. Shown to be a T24 derivative (PubMed=3708594, PubMed=8105864, PubMed=20143388).
Part of: BLA-40 bladder carcinoma cell line panel.
Part of: UBC-40 urothelial bladder cancer cell line index.
Doubling time: 21 hours (PubMed=3708594).
Omics: CNV analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0554 (T24)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): PubMed=11416159

Markers:
AmelogeninX
D18S5116,18
D21S1129
D8S117914
FGA22
TH016
vWA17
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations-v8_0.pdf
Publications

PubMed=7262169; DOI=10.1016/0014-2964(81)90123-7
Vilien M., Wolf H., Rasmussen F.
Immunological characterization of cell lines establishing from malignant and normal human urothelium.
Eur. J. Cancer 17:321-327(1981)

PubMed=6546195; DOI=10.1007/BF00121494
Schroyens W., Mareel M.M., Dragonetti C.
In vitro invasiveness of human bladder cancer from cell lines and biopsy specimens.
Clin. Exp. Metastasis 1:153-162(1983)

PubMed=6826254; DOI=10.1002/ijc.2910310308
Paulie S., Hansson Y., Lundblad M.L., Perlmann P.
Lectins as probes for identification of tumor-associated antigens on urothelial and colonic carcinoma cell lines.
Int. J. Cancer 31:297-303(1983)

PubMed=3708594
Masters J.R.W., Hepburn P.J., Walker L., Highman W.J., Trejdosiewicz L.K., Povey S., Parkar M., Hill B.T., Riddle P.R., Franks L.M.
Tissue culture model of transitional cell carcinoma: characterization of twenty-two human urothelial cell lines.
Cancer Res. 46:3630-3636(1986)

PubMed=8105864; DOI=10.1038/bjc.1993.449
Christensen B., Hansen C., Debiec-Rychter M., Kieler J., Ottensen S., Schmidt J.
Identity of tumorigenic human urothelial cell lines and 'spontaneously' transformed sublines.
Br. J. Cancer 68:879-884(1993)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=24018021; DOI=10.1016/j.eururo.2013.08.052
Allory Y., Beukers W., Sagrera A., Flandez M., Marques M., Marquez M., van der Keur K.A., Dyrskjot L., Lurkin I., Vermeij M., Carrato A., Lloreta J., Lorente J.A., Carrillo-de-Santa-Pau E., Masius R.G., Kogevinas M., Steyerberg E.W., van Tilborg A.A.G., Abas C., Orntoft T.F., Zuiverloon T.C.M., Malats N., Zwarthoff E.C., Real F.X.
Telomerase reverse transcriptase promoter mutations in bladder cancer: high frequency across stages, detection in urine, and lack of association with outcome.
Eur. Urol. 65:360-366(2014)

PubMed=25997541; DOI=10.1186/s12864-015-1450-3
Earl J., Rico D., Carrillo-de-Santa-Pau E., Rodriguez-Santiago B., Mendez-Pertuz M., Auer H., Gomez G., Grossman H.B., Pisano D.G., Schulz W.A., Perez-Jurado L.A., Carrato A., Theodorescu D., Chanock S., Valencia A., Real F.X.
The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.
BMC Genomics 16:403-403(2015)

Cross-references
Biological sample resources BioSample; SAMN03151943
Gene expression databases GEO; GSM1574544
Polymorphism and mutation databases Cosmic; 925829
Cosmic; 2037947