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Cellosaurus Hu609T (CVCL_8241)

[Text version]

Cell line name Hu609T
Synonyms Hu 609T; HU 609 T
Accession CVCL_8241
Resource Identification Initiative To cite this cell line use: Hu609T (RRID:CVCL_8241)
Comments Problematic cell line: Contaminated. Parent cell line (Hu609) has been shown to be a J82 derivative.
Sequence variations Mutation; HGNC; 583; APC; Simple; p.Ser770Pro (c.2308T>C); ClinVar=VCV000140988; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 8975; PIK3CA; Simple; p.Pro124Leu (c.371C>T); Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 9588; PTEN; Simple; p.Asn212fs*1 (c.635_1212del578); Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 9884; RB1; Simple; c.2107-2A>G; ClinVar=VCV000013077; Zygosity=Homozygous; Note=Splice acceptor mutation (from parent cell line).
Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Glu271Lys (c.811G>A); ClinVar=VCV000406566; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Lys320Asn (c.960G>C); Zygosity=Heterozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_8240 (Hu609)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=7262169; DOI=10.1016/0014-2964(81)90123-7
Vilien M., Wolf H., Rasmussen F.
Immunological characterization of cell lines establishing from malignant and normal human urothelium.
Eur. J. Cancer 17:321-327(1981)

PubMed=6546195; DOI=10.1007/BF00121494
Schroyens W., Mareel M.M., Dragonetti C.
In vitro invasiveness of human bladder cancer from cell lines and biopsy specimens.
Clin. Exp. Metastasis 1:153-162(1983)

PubMed=8105864; DOI=10.1038/bjc.1993.449
Christensen B., Hansen C., Debiec-Rychter M., Kieler J., Ottensen S., Schmidt J.
Identity of tumorigenic human urothelial cell lines and 'spontaneously' transformed sublines.
Br. J. Cancer 68:879-884(1993)

PubMed=8900435; DOI=10.1002/(SICI)1097-0215(19961009)68:2<239::AID-IJC17>3.0.CO;2-5
Klopocki A.G., Krop-Watorek A., Dus D., Ugorski M.
Adhesion of human uroepithelial cells to E-selectin: possible involvement of sialosyl LewisA-ganglioside.
Int. J. Cancer 68:239-244(1996)

Cross-references
Other Wikidata; Q54896704
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number16