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Cellosaurus SCLC-24H (CVCL_8262)

Cell line name SCLC-24H
Synonyms MAR-24H; MAR 24H; MAR24H; 24H
Accession CVCL_8262
Resource Identification Initiative To cite this cell line use: SCLC-24H (RRID:CVCL_8262)
Comments Problematic cell line: Contaminated. Shown to be a SCLC-21H (or SCLC-22H) derivative (PubMed=10508494; PubMed=20143388).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00159.
Population: Caucasian.
Doubling time: 70-75 hours (Note=Depending on growth medium) (PubMed=3029138).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0024 (SCLC-21H)
Sex of cell Male
Age at sampling 46Y
Category Cancer cell line
STR profile Source(s): PubMed=24586258

Markers:
AmelogeninX,Y
CSF1PO10
D3S135815
D5S81811,12
D7S82011
D8S117912,13
D13S31712
D16S53912
D18S5114,15
D21S1129,31.2
FGA22,23
Penta D9
Penta E12,13
TH019.3
TPOX8,9
vWA17

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
Publications

PubMed=2438285; DOI=10.1007/BF00396382
Bepler G., Jaques G., Koehler A., Gropp C., Havemann K.
Markers and characteristics of human SCLC cell lines. Neuroendocrine markers, classical tumor markers, and chromosomal characteristics of permanent human small cell lung cancer cell lines.
J. Cancer Res. Clin. Oncol. 113:253-259(1987)

PubMed=3029138; DOI=10.1007/BF00389964
Bepler G., Jaques G., Neumann K., Aumuller G., Gropp C., Havemann K.
Establishment, growth properties, and morphological characteristics of permanent human small cell lung cancer cell lines.
J. Cancer Res. Clin. Oncol. 113:31-40(1987)

PubMed=2473086; DOI=10.1242/jcs.91.1.91
Broers J.L.V., Rot M.K., Oostendorp T., Bepler G., de Leij L.F.M.H., Carney D.N., Vooijs G.P., Ramaekers F.C.S.
Spontaneous changes in intermediate filament protein expression patterns in lung cancer cell lines.
J. Cell Sci. 91:91-108(1988)

PubMed=1845952; DOI=10.1002/1097-0142(19910201)67:3<619::AID-CNCR2820670317>3.0.CO;2-Y
Broers J.L.V., Mijnheere E.P., Rot M.K., Schaart G., Sijlmans A., Boerman O.C., Ramaekers F.C.S.
Novel antigens characteristic of neuroendocrine malignancies.
Cancer 67:619-633(1991)

PubMed=9744504; DOI=10.1038/bjc.1998.553
Damstrup L., Voldborg B.G.R., Spang-Thomsen M., Brunner N., Poulsen H.S.
In vitro invasion of small-cell lung cancer cell lines correlates with expression of epidermal growth factor receptor.
Br. J. Cancer 78:631-640(1998)

PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2
MacLeod R.A.F., Dirks W.G., Matsuo Y., Kaufmann M., Milch H., Drexler H.G.
Widespread intraspecies cross-contamination of human tumor cell lines arising at source.
Int. J. Cancer 83:555-563(1999)

PubMed=11414198; DOI=10.1007/s004320000207
Lahm H., Andre S., Hoeflich A., Fischer J.R., Sordat B., Kaltner H., Wolf E., Gabius H.-J.
Comprehensive galectin fingerprinting in a panel of 61 human tumor cell lines by RT-PCR and its implications for diagnostic and therapeutic procedures.
J. Cancer Res. Clin. Oncol. 127:375-386(2001)

PubMed=12712436; DOI=10.1002/ijc.11106
Hansen L.T., Lundin C., Spang-Thomsen M., Petersen L.N., Helleday T.
The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer.
Int. J. Cancer 105:472-479(2003)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=24586258; DOI=10.1371/journal.pone.0086910
Murmann-Konda T., Carrillo-Garcia C., Veit N., Courts C., Glassmann A., Janzen V., Madea B., Reinartz M., Harzen A., Nowak M., Perner S., Winter J., Probstmeier R.
Staurosporine and extracellular matrix proteins mediate the conversion of small cell lung carcinoma cells into a neuron-like phenotype.
PLoS ONE 9:E86910-E86910(2014)

Cross-references
Cell line collections (Providers) CLS; 300177
Biological sample resources BioSample; SAMN03151913
Encyclopedic resources Wikidata; Q54952446
Polymorphism and mutation databases Cosmic; 2648018
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number21