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Cellosaurus SQ-5 (CVCL_8273)

[Text version]

Cell line name SQ-5
Synonyms Sq-5; SQ5
Accession CVCL_8273
Resource Identification Initiative To cite this cell line use: SQ-5 (RRID:CVCL_8273)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=16643607; PubMed=20143388). Originally thought to originate from a lung carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00269.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from sampling site: Uterus; cervix.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v11_distribution.xlsx
Publications

PubMed=10358721; DOI=10.18926/AMO/31626
Matsushita A., Tabata M., Ueoka H., Kiura K., Shibayama T., Aoe K., Kohara H., Harada M.
Establishment of a drug sensitivity panel using human lung cancer cell lines.
Acta Med. Okayama 53:67-75(1999)

PubMed=16105816; DOI=10.1158/0008-5472.CAN-05-0331
Nagai Y., Miyazawa H., Huqun X., Tanaka T., Udagawa K., Kato M., Fukuyama S., Yokote A., Kobayashi K., Kanazawa M., Hagiwara K.
Genetic heterogeneity of the epidermal growth factor receptor in non-small cell lung cancer cell lines revealed by a rapid and sensitive detection system, the peptide nucleic acid-locked nucleic acid PCR clamp.
Cancer Res. 65:7276-7282(2005)

PubMed=16643607; DOI=10.1111/j.1749-0774.2005.00007.x
Yoshino K., Iimura E., Saijo K., Iwase S., Fukami K., Ohno T., Obata Y., Nakamura Y.
Essential role for gene profiling analysis in the authentication of human cell lines.
Hum. Cell 19:43-48(2006)

PubMed=19472407; DOI=10.1002/humu.21028
Blanco R., Iwakawa R., Tang M., Kohno T., Angulo B., Pio R., Montuenga L.M., Minna J.D., Yokota J., Sanchez-Cespedes M.
A gene-alteration profile of human lung cancer cell lines.
Hum. Mutat. 30:1199-1206(2009)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line collections RCB; RCB0110 - Discontinued
Biological sample resources BioSample; SAMN03151759
Encyclopedic resources Wikidata; Q54955605
Experimental variables resources EFO; EFO_0002861
Polymorphism and mutation databases Cosmic; 946076
Cosmic; 1219091
Cosmic; 1239914
Cosmic; 1571743
Entry history
Entry creation04-Apr-2012
Last entry update23-Sep-2021
Version number20