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Cellosaurus CoLo-TC (CVCL_8290)

[Text version]

Cell line name CoLo-TC
Synonyms CoLoTC
Accession CVCL_8290
Resource Identification Initiative To cite this cell line use: CoLo-TC (RRID:CVCL_8290)
Comments Problematic cell line: Contaminated. Shown to be a COLO 205 derivative (PubMed=20143388).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00300.
Sequence variations Homozygous for APC p.Thr1556fs*3 (c.4666_4667insA) (from parent cell line).
Heterozygous for BRAF p.Val600Glu (c.1799T>A) (ClinVar=VCV000013961) (from parent cell line).
Homozygous for CTNNB1 p.Asn287Ser (c.860A>G) (from parent cell line).
Homozygous for TP53 p.Tyr103fs*37 (c.308_321delTGTGTAACAGTTCC) (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0218 (COLO 205)
Sex of cell Male
Age at sampling 70Y
Category Cancer cell line
STR profile Source(s): TKG

Markers:
AmelogeninX
CSF1PO11,12
D5S81810,13
D7S8209,10
D13S31710,12
D16S53912,13
TH018,9
TPOX11
vWA15

Run an STR similarity search on this cell line
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v10_distribution.xlsx
Publications

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line collections RCB; RCB1984 - Discontinued
TKG; TKG 0404
Biological sample resources BioSample; SAMN03151626
Other Wikidata; Q54814178
Polymorphism and mutation databases Cosmic; 1066208
Entry history
Entry creation04-Apr-2012
Last entry update02-Jul-2020
Version number17