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Cellosaurus Ger (CVCL_8353)

Cell line name Ger
Synonyms GER
Accession CVCL_8353
Resource Identification Initiative To cite this cell line use: Ger (RRID:CVCL_8353)
Comments Doubling time: 36 hours (Note=At 11th passage) (PubMed=435363).
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=11787853).
  • Gene deletion; HGNC; 6770; SMAD4; Zygosity=Homozygous (PubMed=11787853).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (PubMed=11787853).
  • Mutation; HGNC; 11998; TP53; Simple; p.Val272Leu (c.814G>T); ClinVar=VCV000012358; Zygosity=Unspecified (PubMed=11787853).
Disease Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=435363; DOI=10.1038/bjc.1979.24
Grant A.G., Duke D., Hermon-Taylor J.
Establishment and characterization of primary human pancreatic carcinoma in continuous cell culture and in nude mice.
Br. J. Cancer 39:143-151(1979)

PubMed=11787853; DOI=10.1007/s004280100474
Moore P.S., Sipos B., Orlandini S., Sorio C., Real F.X., Lemoine N.R., Gress T.M., Bassi C., Kloppel G., Kalthoff H., Ungefroren H., Lohr J.-M., Scarpa A.
Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4.
Virchows Arch. 439:798-802(2001)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8353
Anatomy/cell type resources BTO; BTO:0002865
Encyclopedic resources Wikidata; Q54835727
Polymorphism and mutation databases Cosmic; 710856
IARC_TP53; 16740
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number16