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Cellosaurus RS-1 [Human leukemia] (CVCL_8423)

Cell line name RS-1 [Human leukemia]
Accession CVCL_8423
Resource Identification Initiative To cite this cell line use: RS-1 [Human leukemia] (RRID:CVCL_8423)
Comments Problematic cell line: Contaminated. Shown to be a K-562 derivative (PubMed=12592342; PubMed=20143388). Originally thought to originate from a 2 year old child suffering from acute megakaryoblastic leukemia (AML-M7).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00264.
Derived from sampling site: Pleural effusion.
Sequence variations Homozygous for TP53 p.Gln136fs*13 (c.406_407insC) (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v9_distribution.xlsx
Publications

PubMed=9210910; DOI=10.1159/000203557
Skinnider L.F., Pabello P., Zheng C.Y.
Characteristics of a cell line established from a case of acute megakaryoblastic leukemia.
Acta Haematol. 98:26-31(1997)

PubMed=12592342; DOI=10.1038/sj.leu.2402799
Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F.
False leukemia-lymphoma cell lines: an update on over 500 cell lines.
Leukemia 17:416-426(2003)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Biological sample resources BioSample; SAMN03151812
Other Wikidata; Q54951292