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Cellosaurus HIMeg-1 (CVCL_8439)

Cell line name HIMeg-1
Synonyms HIMEG-1
Accession CVCL_8439
Resource Identification Initiative To cite this cell line use: HIMeg-1 (RRID:CVCL_8439)
Comments Problematic cell line: Contaminated. Shown to be a HL-60 derivative (PubMed=12592342; PubMed=20143388).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00208.
Derived from sampling site: Peripheral blood.
Sequence variations Homozygous for CDKN2A p.Arg80Ter (c.238C>T) (from parent cell line).
Heterozygous for NRAS p.Gln61Leu (c.182A>T) (from parent cell line).
Disease Adult acute myeloid leukemia (NCIt: C9154)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0002 (HL-60)
Sex of cell Female
Age at sampling 35Y
Category Cancer cell line
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v9_distribution.xlsx

Cheng T., Erickson-Miller C.L., Li C., Cardier J., Wang Y., Dempsey J., Mogle M., Barbera E., Murphy M.J. Jr., Dai W.
HIMeg-1, a cell line derived from a CML patient, is capable of monocytic and megakaryocytic differentiation.
Leukemia 9:1257-1263(1995)

PubMed=12592342; DOI=10.1038/sj.leu.2402799
Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F.
False leukemia-lymphoma cell lines: an update on over 500 cell lines.
Leukemia 17:416-426(2003)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Biological sample resources BioSample; SAMN03151774
Other Wikidata; Q54889552