Cellosaurus cell line C918 (CVCL_8471)

• Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (PubMed=22383533).
  

PubMed=8683940
Daniels K.J., Boldt H.C., Martin J.A., Gardner L.M., Meyer M., Folberg R.
Expression of type VI collagen in uveal melanoma: its role in pattern formation and tumor progression.
Lab. Invest. 75:55-66(1996)

PubMed=10952317; DOI=10.1038/35020115
Bittner M., Meltzer P.S., Chen Y.-D., Jiang Y., Seftor E.A., Hendrix M.J.C., Radmacher M.D., Simon R.M., Yakhini Z., Ben-Dor A., Sampas N., Dougherty E., Wang E., Marincola F.M., Gooden C., Lueders J., Glatfelter A., Pollock P.M., Carpten J.D., Gillanders E.M., Leja D., Dietrich K., Beaudry C., Berens M.E., Alberts D.S., Sondak V.K., Hayward N.K., Trent J.M.
Molecular classification of cutaneous malignant melanoma by gene expression profiling.
Nature 406:536-540(2000)

PubMed=18689700; DOI=10.1167/iovs.08-2324
Folberg R., Kadkol S.S., Frenkel S., Valyi-Nagy K., Jager M.J., Pe'er J., Maniotis A.J.
Authenticating cell lines in ophthalmic research laboratories.
Invest. Ophthalmol. Vis. Sci. 49:4697-4701(2008)

PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676
Dutton-Regester K., Irwin D., Hunt P., Aoude L.G., Tembe V., Pupo G.M., Lanagan C., Carter C.D., O'Connor L., O'Rourke M., Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K.
A high-throughput panel for identifying clinically relevant mutation profiles in melanoma.
Mol. Cancer Ther. 11:888-897(2012)