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Cellosaurus Mel20-06-045 (CVCL_8474)

[Text version]
Cell line name Mel20-06-045
Synonyms MEL20-06-045
Accession CVCL_8474
Resource Identification Initiative To cite this cell line use: Mel20-06-045 (RRID:CVCL_8474)
Comments Omics: Transcriptome analysis by microarray.
Sequence variations
  • Mutation; HGNC; 4390; GNAQ; Simple; p.Gln209Pro (c.626A>C); ClinVar=VCV000375957; Zygosity=Heterozygous (PubMed=21386926).
Disease Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=21386926
Burgess B.L., Rao N.P., Eskin A., Nelson S.F., McCannel T.A.
Characterization of three cell lines derived from fine needle biopsy of choroidal melanoma with metastatic outcome.
Mol. Vis. 17:607-615(2011)

PubMed=22515704; DOI=10.1186/1476-4598-11-22
von Euw E.M., Atefi M., Attar N., Chu C., Zachariah S., Burgess B.L., Mok S., Ng C., Wong D.J.L., Chmielowski B., Lichter D.I., Koya R.C., McCannel T.A., Izmailova E., Ribas A.
Antitumor effects of the investigational selective MEK inhibitor TAK733 against cutaneous and uveal melanoma cell lines.
Mol. Cancer 11:22.1-22.9(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8474
Encyclopedic resources Wikidata; Q54905157
Polymorphism and mutation databases Cosmic; 1665024
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number14