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Cellosaurus Kasumi-10 (CVCL_8485)

[Text version]
Cell line name Kasumi-10
Synonyms KASUMI-10
Accession CVCL_8485
Resource Identification Initiative To cite this cell line use: Kasumi-10 (RRID:CVCL_8485)
Comments Population: Japanese and Korean.
Karyotypic information: While originating from a female patient, it has a XXY karyotype that could be explained by a disorder of sexual development (PubMed=32180206).
Omics: Deep quantitative proteome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by RNAseq.
Miscellaneous: STR profile from personal communication of Leo I.R.
Sequence variations
  • Gene fusion; HGNC; 7132; KMT2A + HGNC; 7134; MLLT1; Name(s)=KMT2A-MLLT1, MLL-MLLT1; MLL-ENL (PubMed=32180206; PubMed=35354797).
  • Mutation; HGNC; 3765; FLT3; Unexplicit; Internal tandem duplication (FLT3-ITD); ClinVar=VCV000016270; Zygosity=Unspecified (PubMed=32180206).
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
B acute lymphoblastic leukemia with t(v;11q23.3) MLL rearranged (NCIt: C80342)
B-lymphoblastic leukemia/lymphoma with t(v;11q23.3) (ORDO: Orphanet_585918)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 6M
Category Cancer cell line
STR profile Source(s): JCRB; Direct_author_submission

Markers:
AmelogeninX,Y
CSF1PO11,12
D1S165615,17
D2S44111,11.3
D2S133819,24
D3S135815,16
D5S81810,12
D7S8208,10
D8S117913,14
D10S124812,15
D12S39118,22
D13S3178,11
D16S5399,10
D18S5113
D19S43315.2,16
D21S1130
D22S104515,17
DYS3919
FGA22,27.2
SE3320,26.2
TH016,9
TPOX11,12
vWA17,19

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Publications

PubMed=32180206; DOI=10.1007/s13577-020-00347-5
Kasai F., Asou H., Ozawa M., Kobayashi K., Kuramitsu H., Satoh M., Kohara A., Kaneko Y., Kawamura M.
Kasumi leukemia cell lines: characterization of tumor genomes with ethnic origin and scales of genomic alterations.
Hum. Cell 33:868-876(2020)

PubMed=35354797; DOI=10.1038/s41467-022-29224-5
Leo I.R., Aswad L., Stahl M., Kunold E., Post F., Erkers T., Struyf N., Mermelekas G., Joshi R.N., Gracia-Villacampa E., Ostling P., Kallioniemi O.-P., Pokrovskaja Tamm K., Siavelis I., Lehtio J., Vesterlund M., Jafari R.
Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines.
Nat. Commun. 13:1691.1-1691.19(2022)

Cross-references
Cell line collections (Providers) JCRB; JCRB1410
Encyclopedic resources Wikidata; Q54899515
Gene expression databases GEO; GSM4254138
GEO; GSM5137757
Proteomic databases PRIDE; PXD023662
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number18