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Cellosaurus Kasumi-7 (CVCL_8486)

[Text version]
Cell line name Kasumi-7
Synonyms Kasumi 7; Kasumi7
Accession CVCL_8486
Resource Identification Initiative To cite this cell line use: Kasumi-7 (RRID:CVCL_8486)
Comments Population: Japanese.
Omics: SNP array analysis.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=32180206).
  • Gene fusion; HGNC; 6997; MEF2D + HGNC; 17011; HNRNPUL1; Name(s)=MEF2D-HNRNPUL1 (PubMed=32504922).
Disease Adult B acute lymphoblastic leukemia (NCIt: C9143)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 29Y
Category Cancer cell line
STR profile Source(s): JCRB

Markers:
AmelogeninX
CSF1PO12
D5S81812,13
D7S8209,10
D13S3178,10
D16S5399
TH016
TPOX8,11
vWA14,18

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Publications

PubMed=32180206; DOI=10.1007/s13577-020-00347-5
Kasai F., Asou H., Ozawa M., Kobayashi K., Kuramitsu H., Satoh M., Kohara A., Kaneko Y., Kawamura M.
Kasumi leukemia cell lines: characterization of tumor genomes with ethnic origin and scales of genomic alterations.
Hum. Cell 33:868-876(2020)

PubMed=32504922; DOI=10.1016/j.biopha.2020.110330
Tange N., Hayakawa F., Yasuda T., Odaira K., Yamamoto H., Hirano D., Sakai T., Terakura S., Tsuzuki S., Kiyoi H.
Staurosporine and venetoclax induce the caspase-dependent proteolysis of MEF2D-fusion proteins and apoptosis in MEF2D-fusion (+) ALL cells.
Biomed. Pharmacother. 128:110330-110330(2020)

PubMed=35124168; DOI=10.1016/j.jsbmb.2022.106068
Tamai M., Kasai S., Akahane K., Thu T.N., Kagami K., Komatsu C., Abe M., Watanabe A., Goi K., Miyake K., Inaba T., Takita J., Goto H., Minegishi M., Iwamoto S., Sugita K., Inukai T.
Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia.
J. Steroid Biochem. Mol. Biol. 218:106068.1-106068.12(2022)

Cross-references
Cell line collections (Providers) JCRB; JCRB1401
Encyclopedic resources Wikidata; Q54899524
Gene expression databases GEO; GSM4254135
Entry history
Entry creation04-Apr-2012
Last entry update30-Jan-2024
Version number18