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Cellosaurus Kasumi-9 (CVCL_8488)

[Text version]
Cell line name Kasumi-9
Synonyms KASUMI-9; Kasumi9
Accession CVCL_8488
Resource Identification Initiative To cite this cell line use: Kasumi-9 (RRID:CVCL_8488)
Comments Population: Japanese.
Omics: Deep quantitative proteome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by RNAseq.
Miscellaneous: STR profile from personal communication of Leo I.R.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=32180206).
  • Gene fusion; HGNC; 6997; MEF2D + HGNC; 17011; HNRNPUL1; Name(s)=MEF2D-HNRNPUL1 (PubMed=32504922; PubMed=35354797).
Disease Adult B acute lymphoblastic leukemia (NCIt: C9143)
Precursor B-cell acute lymphoblastic leukemia (ORDO: Orphanet_99860)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 19Y
Category Cancer cell line
STR profile Source(s): JCRB; Direct_author_submission

Markers:
AmelogeninX,Y
CSF1PO11
D1S165616,18.3
D2S44110,14
D2S133817,19
D3S135816,17
D5S81812
D7S8208,10
D8S117914,17
D10S124812,14
D12S39119,24
D13S3178,9
D16S53911,13
D18S5113,15
D19S43313,14.2
D21S1130
D22S104515,16
DYS39110
FGA22,23
SE3326.2,30.2
TH017,9
TPOX8
vWA17

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Publications

PubMed=32180206; DOI=10.1007/s13577-020-00347-5
Kasai F., Asou H., Ozawa M., Kobayashi K., Kuramitsu H., Satoh M., Kohara A., Kaneko Y., Kawamura M.
Kasumi leukemia cell lines: characterization of tumor genomes with ethnic origin and scales of genomic alterations.
Hum. Cell 33:868-876(2020)

PubMed=32504922; DOI=10.1016/j.biopha.2020.110330
Tange N., Hayakawa F., Yasuda T., Odaira K., Yamamoto H., Hirano D., Sakai T., Terakura S., Tsuzuki S., Kiyoi H.
Staurosporine and venetoclax induce the caspase-dependent proteolysis of MEF2D-fusion proteins and apoptosis in MEF2D-fusion (+) ALL cells.
Biomed. Pharmacother. 128:110330-110330(2020)

PubMed=35124168; DOI=10.1016/j.jsbmb.2022.106068
Tamai M., Kasai S., Akahane K., Thu T.N., Kagami K., Komatsu C., Abe M., Watanabe A., Goi K., Miyake K., Inaba T., Takita J., Goto H., Minegishi M., Iwamoto S., Sugita K., Inukai T.
Glucocorticoid receptor gene mutations confer glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia.
J. Steroid Biochem. Mol. Biol. 218:106068.1-106068.12(2022)

PubMed=35354797; DOI=10.1038/s41467-022-29224-5
Leo I.R., Aswad L., Stahl M., Kunold E., Post F., Erkers T., Struyf N., Mermelekas G., Joshi R.N., Gracia-Villacampa E., Ostling P., Kallioniemi O.-P., Pokrovskaja Tamm K., Siavelis I., Lehtio J., Vesterlund M., Jafari R.
Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines.
Nat. Commun. 13:1691.1-1691.19(2022)

Cross-references
Cell line collections (Providers) JCRB; JCRB1409
Encyclopedic resources Wikidata; Q54899526
Gene expression databases GEO; GSM4254137
GEO; GSM5137721
GEO; GSM5137759
Proteomic databases PRIDE; PXD023662
Entry history
Entry creation04-Apr-2012
Last entry update30-Jan-2024
Version number16