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Cellosaurus AR-EcoScreen (CVCL_8544)

[Text version]
Cell line name AR-EcoScreen
Accession CVCL_8544
Resource Identification Initiative To cite this cell line use: AR-EcoScreen (RRID:CVCL_8544)
Comments Biotechnology: Used in the AR STTA bioassay for the rapid evaluation of in vitro androgen receptor transcriptional activation.
Characteristics: The luciferase reporter gene is under the control of a construct bearing four tandem repeats of a prostate C3 gene androgen-responsive element driven by a minimal heat shock protein promoter.
Transfected with: HGNC; 644; AR.
Transfected with: UniProtKB; P27652; Renilla-type luciferase.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0214 (CHO-K1)
Children:
CVCL_VN86 (AR-EcoScreen GR KO M1)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Web pages https://www.oecd.org/env/ehs/testing/Doc-id-381084-Draft-TG-AR-STTA-clean.pdf
Publications

PubMed=15110108; DOI=10.1016/j.fct.2004.02.011
Satoh K., Ohyama K., Aoki N., Iida M., Nagai F.
Study on anti-androgenic effects of bisphenol a diglycidyl ether (BADGE), bisphenol F diglycidyl ether (BFDGE) and their derivatives using cells stably transfected with human androgen receptor, AR-EcoScreen.
Food Chem. Toxicol. 42:983-993(2004)

PubMed=15713541; DOI=10.1016/j.tiv.2004.10.008
Araki N., Ohno K., Takeyoshi M., Iida M.
Evaluation of a rapid in vitro androgen receptor transcriptional activation assay using AR-EcoScreen cells.
Toxicol. In Vitro 19:335-352(2005)

Cross-references
Cell line collections (Providers) JCRB; JCRB1328
Encyclopedic resources Wikidata; Q54750350
Entry history
Entry creation04-Apr-2012
Last entry update30-Jan-2024
Version number10