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Cellosaurus HepG2-GS-CYP3A4 (CVCL_8560)

[Text version]
Cell line name HepG2-GS-CYP3A4
Synonyms GS-3A4-HepG2
Accession CVCL_8560
Resource Identification Initiative To cite this cell line use: HepG2-GS-CYP3A4 (RRID:CVCL_8560)
Comments Population: Caucasian.
Transfected with: HGNC; 2637; CYP3A4.
Transfected with: HGNC; 4341; GLUL.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
STR profile Source(s): JCRB

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S81811,12
D7S82010
D13S3179,13
D16S53912
TH019
TPOX8,9
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=15903254; DOI=10.1021/bp049757a
Omasa T., Kim K., Hiramatsu S., Katakura Y., Kishimoto M., Enosawa S., Ohtake H.
Construction and evaluation of drug-metabolizing cell line for bioartificial liver support system.
Biotechnol. Prog. 21:161-167(2005)

Cross-references
Cell line collections (Providers) JCRB; JCRB1371
JCRB; NIHS0617 - Discontinued
Cell line databases/resources cancercelllines; CVCL_8560
Encyclopedic resources Wikidata; Q54882851
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number21