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Cellosaurus HOC605 (CVCL_8698)

Cell line name HOC605
Accession CVCL_8698
Resource Identification Initiative To cite this cell line use: HOC605 (RRID:CVCL_8698)
Comments Population: Japanese.
Derived from site: In situ; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Unspecified (PubMed=1570156).
Disease Oral cavity squamous cell carcinoma (NCIt: C4833)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=1570156
Sakai E., Tsuchida N.
Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumor-suppressor genes.
Oncogene 7:927-933(1992)

PubMed=1624295; DOI=10.1002/hed.2880140103
Rikimaru K., Tadokoro K., Yamamoto T., Enomoto S., Tsuchida N.
Gene amplification and overexpression of epidermal growth factor receptor in squamous cell carcinoma of the head and neck.
Head Neck 14:8-13(1992)

PubMed=18097548; DOI=10.3892/ijo.32.1.101
Murugan A.K., Hong N.T., Fukui Y., Munirajan A.K., Tsuchida N.
Oncogenic mutations of the PIK3CA gene in head and neck squamous cell carcinomas.
Int. J. Oncol. 32:101-111(2008)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8698
Encyclopedic resources Wikidata; Q54890114
Polymorphism and mutation databases Cosmic; 1123033
IARC_TP53; 1097
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number14