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Cellosaurus HOC719-PE (CVCL_8702)

[Text version]
Cell line name HOC719-PE
Synonyms HOC719-Positive E-cadherin
Accession CVCL_8702
Resource Identification Initiative To cite this cell line use: HOC719-PE (RRID:CVCL_8702)
Comments Population: Japanese.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Met1043Val (c.3127A>G); ClinVar=VCV000376485; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Asp281Glu (c.843C>G); ClinVar=VCV000376587; Zygosity=Unspecified (from parent cell line).
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_8700 (HOC719)
Category Cancer cell line
Publications

PubMed=11120485; DOI=10.1016/S1368-8375(00)00059-2
Yokoyama K., Kamata N., Hayashi E., Hoteiya T., Ueda N., Fujimoto R., Nagayama M.
Reverse correlation of E-cadherin and snail expression in oral squamous cell carcinoma cells in vitro.
Oral Oncol. 37:65-71(2001)

PubMed=12632084; DOI=10.3892/ijo.22.4.891
Yokoyama K., Kamata N., Fujimoto R., Tsutsumi S., Tomonari M., Taki M., Hosokawa H., Nagayama M.
Increased invasion and matrix metalloproteinase-2 expression by Snail-induced mesenchymal transition in squamous cell carcinomas.
Int. J. Oncol. 22:891-898(2003)

Cross-references
Encyclopedic resources Wikidata; Q54890118
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number14