| Cell line name |
HOC927 |
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| Accession |
CVCL_8704 |
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| Resource Identification Initiative |
To cite this cell line use: HOC927 (RRID:CVCL_8704) |
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| Comments |
Derived from site: In situ; Lymph node; UBERON=UBERON_0000027. |
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| Sequence variations |
- Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Homozygous (PubMed=18097548).
- Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (PubMed=1570156).
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| Disease |
Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Category |
Cancer cell line |
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| Publications | PubMed=1570156
Sakai E., Tsuchida N.
Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumor-suppressor genes.
Oncogene 7:927-933(1992) PubMed=1624295; DOI=10.1002/hed.2880140103
Rikimaru K., Tadokoro K., Yamamoto T., Enomoto S., Tsuchida N.
Gene amplification and overexpression of epidermal growth factor receptor in squamous cell carcinoma of the head and neck.
Head Neck 14:8-13(1992) PubMed=10069537; DOI=10.1111/j.1600-0714.1999.tb02006.x
Hoteiya T., Hayashi E., Satomura K., Kamata N., Nagayama M.
Expression of E-cadherin in oral cancer cell lines and its relationship to invasiveness in SCID mice in vivo.
J. Oral Pathol. Med. 28:107-111(1999) PubMed=18097548; DOI=10.3892/ijo.32.1.101
Murugan A.K., Hong N.T., Fukui Y., Munirajan A.K., Tsuchida N.
Oncogenic mutations of the PIK3CA gene in head and neck squamous cell carcinomas.
Int. J. Oncol. 32:101-111(2008) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_8704
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| Encyclopedic resources |
Wikidata; Q54890121
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| Polymorphism and mutation databases |
Cosmic; 1123035
IARC_TP53; 24377
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| Entry history |
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| Entry creation | 04-Apr-2012 |
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| Last entry update | 05-Oct-2023 |
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| Version number | 17 |
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