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Cellosaurus HS-Sch-2 (CVCL_8718)

[Text version]

Cell line name HS-Sch-2
Synonyms HS-sch-2
Accession CVCL_8718
Resource Identification Initiative To cite this cell line use: HS-Sch-2 (RRID:CVCL_8718)
Comments Doubling time: ~56 hours (PubMed=10891546).
Sequence variations TP53 p.Arg273His (c.818G>A) (ClinVar=VCV000012366) (PubMed=10891546).
Disease Malignant peripheral nerve sheath tumor (NCIt: C3798)
Malignant peripheral nerve sheath tumor (ORDO: Orphanet_3148)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
STR profile Source(s): PubMed=28556483; RCB

Markers:
AmelogeninX
CSF1PO11,13
D2S133820
D3S135818
D5S81813
D7S8208,11
D8S117914
D13S31711
D16S53911,12
D18S5113,14
D19S43314.2
D21S1129,30
FGA23,26
TH016,7
TPOX8
vWA15,16

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Publications

PubMed=10891546; DOI=10.3892/ijo.17.2.347
Sonobe H., Takeuchi T., Furihata M., Taguchi T., Kawai A., Ohjimi Y., Iwasaki H., Kaneko Y., Ohtsuki Y.
A new human malignant peripheral nerve sheath tumour-cell line, HS-Sch-2, harbouring p53 point mutation.
Int. J. Oncol. 17:347-352(2000)

PubMed=28556483; DOI=10.1002/1878-0261.12086
Kolberg M., Bruun J., Murumagi A., Mpindi J.P., Bergsland C.H., Holand M., Eilertsen I.A., Danielsen S.A., Kallioniemi O., Lothe R.A.
Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors.
Mol. Oncol. 11:1156-1171(2017)

DOI=10.1093/noajnl/vdz049
Pemov A., Li H., Presley W., Wallace M.R., Miller D.T.
Genetics of human malignant peripheral nerve sheath tumors.
Neurooncol. Adv. 1:vdz049-vdz049(2019)

Cross-references
Cell line collections BCRJ; 0376
RCB; RCB2230
Ontologies CLO; CLO_0050146
Biological sample resources BioSample; SAMN03472028
Other Wikidata; Q54896291
Entry history
Entry creation04-Apr-2012
Last entry update02-Jul-2020
Version number15