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Cellosaurus OCI-Ly12 (CVCL_8796)

Cell line name OCI-Ly12
Synonyms OCI-LY12; OCI-LY-12; OCI-Ly 12; OCI Ly12; OCILY12; Ly12
Accession CVCL_8796
Resource Identification Initiative To cite this cell line use: OCI-Ly12 (RRID:CVCL_8796)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
From: Ontario Cancer Institute (OCI); Toronto; Canada.
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Cys238Arg (c.712T>C); ClinVar=VCV000376576; Zygosity=Unspecified (DepMap).
Disease Grade 1 follicular lymphoma (NCIt: C3465)
Follicular lymphoma (ORDO: Orphanet_545)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 37Y
Category Cancer cell line
Publications

PubMed=3567358; DOI=10.1182/blood.V69.5.1307.1307
Tweeddale M.E., Lim B., Jamal N., Robinson J., Zalcberg J.R., Lockwood G., Minden M.D., Messner H.A.
The presence of clonogenic cells in high-grade malignant lymphoma: a prognostic factor.
Blood 69:1307-1314(1987)

PubMed=8574164; DOI=10.3109/10428199509059672
Chang H., Blondal J.A., Benchimol S., Minden M.D., Messner H.A.
p53 mutations, c-myc and bcl-2 rearrangements in human non-Hodgkin's lymphoma cell lines.
Leuk. Lymphoma 19:165-171(1995)

PubMed=10676951; DOI=10.1038/35000501
Alizadeh A.A., Eisen M.B., Davis R.E., Ma C., Lossos I.S., Rosenwald A., Boldrick J.C., Sabet H., Tran T., Yu X., Powell J.I., Yang L.-M., Marti G.E., Moore T., Hudson J. Jr., Lu L.-S., Lewis D.B., Tibshirani R., Sherlock G., Chan W.C., Greiner T.C., Weisenburger D.D., Armitage J.O., Warnke R.A., Levy R., Wilson W., Grever M.R., Byrd J.C., Botstein D., Brown P.O., Staudt L.M.
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling.
Nature 403:503-511(2000)

PubMed=11807979; DOI=10.1002/gcc.10025
Mehra S., Messner H.A., Minden M.D., Chaganti R.S.K.
Molecular cytogenetic characterization of non-Hodgkin lymphoma cell lines.
Genes Chromosomes Cancer 33:225-234(2002)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8796
Cell_Model_Passport; SIDM01882
DepMap; ACH-001147
Encyclopedic resources Wikidata; Q54931762
Gene expression databases GEO; GSM1990
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number18