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Cellosaurus SJNB-5 (CVCL_8822)

[Text version]

Cell line name SJNB-5
Synonyms SJNB5; SJ-NB5; NB5; NB5-DH; NJF
Accession CVCL_8822
Secondary accession CVCL_1446
Resource Identification Initiative To cite this cell line use: SJNB-5 (RRID:CVCL_8822)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African87.26
Native American0
East Asian, North2.17
East Asian, South0
South Asian0.49
European, North5.14
European, South4.93
Disease Neuroblastoma (NCIt: C3270)
Derived from metastatic site: Bone marrow.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 2Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX
CSF1PO11,12
D5S81812,13
D7S82011
D13S31713
D16S5399,10
TH017,8
TPOX8,11
vWA16,19

Run an STR similarity search on this cell line
Publications

PubMed=6171342
Brodeur G.M., Green A.A., Hayes F.A., Williams K.J., Williams D.L., Tsiatis A.A.
Cytogenetic features of human neuroblastomas and cell lines.
Cancer Res. 41:4678-4686(1981)

PubMed=8516298; DOI=10.1073/pnas.90.12.5539
Johnson M.R., Look A.T., DeClue J.E., Valentine M.B., Lowy D.R.
Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Ras.
Proc. Natl. Acad. Sci. U.S.A. 90:5539-5543(1993)

DOI=10.1007/0-306-46872-7_2
Thiele C.J.
Neuroblastoma.
(In) Human cell culture. Vol. 1. Cancer Cell Lines part 1; Masters J.R.W., Palsson B.O. (eds.); pp.21-53; Kluwer Academic Publishers; New York (1999)

PubMed=10935473; DOI=10.1038/sj.neo.7900010
Kong X.-T., Valentine V.A., Rowe S.T., Valentine M.B., Ragsdale S.T., Jones B.G., Wilkinson D.A., Brodeur G.M., Cohn S.L., Look A.T.
Lack of homozygously inactivated p73 in single-copy MYCN primary neuroblastomas and neuroblastoma cell lines.
Neoplasia 1:80-89(1999)

PubMed=18923524; DOI=10.1038/nature07399
Chen Y., Takita J., Choi Y.L., Kato M., Ohira M., Sanada M., Wang L., Soda M., Kikuchi A., Igarashi T., Nakagawara A., Hayashi Y., Mano H., Ogawa S.
Oncogenic mutations of ALK kinase in neuroblastoma.
Nature 455:971-974(2008)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line databases/resources CCLE; NB5_AUTONOMIC_GANGLIA
Cell_Model_Passport; SIDM00254
Cosmic-CLP; 949176
DepMap; ACH-002283
GDSC; 949176
LINCS_LDP; LCL-1995
Ontologies BTO; BTO:0005072
Chemistry resources ChEMBL-Cells; CHEMBL3308156
ChEMBL-Targets; CHEMBL2366328
PharmacoDB; NB5_991_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM314023
GEO; GSM333810
GEO; GSM1670152
Other Wikidata; Q54953577
Polymorphism and mutation databases Cosmic; 688080
Cosmic; 922662
Cosmic; 949176
Cosmic; 947716
Cosmic; 1037335
Cosmic; 1099132
Cosmic; 1153796
Cosmic; 1526633
Cosmic; 2131586
Entry history
Entry creation06-Jun-2012
Last entry updated06-Sep-2019
Version number23