Cellosaurus EU-1 (CVCL_8857)

Cell line name EU-1
Synonyms 855; Line 855; Emory University-1
Accession CVCL_8857
Resource Identification Initiative To cite this cell line use: EU-1 (RRID:CVCL_8857)
Comments Problematic cell line: Contaminated. Shown to be a Reh derivative (PubMed=12592342, PubMed=20143388).
Derived from sampling site: Peripheral blood.
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1650 (Reh)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): COG

Markers:
AmelogeninX
CSF1PO11,12
D13S31711,13
D16S5398,9,10
D18S5110,14
D19S43312,13
D21S1128,30,31
D2S133820,22
D3S135817,18
D5S81811,13
D7S8209,12,13
D8S117913,15
FGA22,23
TH017
TPOX8
vWA14,15
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations-v8_0.pdf
Publications

PubMed=8152261
Zhou M., Zaki S.R., Ragab A.H., Findley H.W.
Characterization of a myeloperoxidase mRNA(+) acute lymphoblastic leukemia cell line (EU-1/ALL) established from a child with an apparent case of ALL.
Leukemia 8:659-663(1994)

PubMed=7888679
Zhou M., Yeager A.M., Smith S.D., Findley H.W.
Overexpression of the MDM2 gene by childhood acute lymphoblastic leukemia cells expressing the wild-type p53 gene.
Blood 85:1608-1614(1995)

PubMed=9108419
Findley H.W., Gu L., Yeager A.M., Zhou M.
Expression and regulation of Bcl-2, Bcl-xl, and Bax correlate with p53 status and sensitivity to apoptosis in childhood acute lymphoblastic leukemia.
Blood 89:2986-2993(1997)

PubMed=9823951
Zhou M., Gu L., Yeager A.M., Findley H.W.
Sensitivity to Fas-mediated apoptosis in pediatric acute lymphoblastic leukemia is associated with a mutant p53 phenotype and absence of Bcl-2 expression.
Leukemia 12:1756-1763(1998)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=12592342; DOI=10.1038/sj.leu.2402799
Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F.
False leukemia-lymphoma cell lines: an update on over 500 cell lines.
Leukemia 17:416-426(2003)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Biological sample resources BioSample; SAMN03151904