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Cellosaurus FLYA13 (CVCL_8870)

[Text version]

Cell line name FLYA13
Synonyms FLY-A13; FLY-AF-13
Accession CVCL_8870
Resource Identification Initiative To cite this cell line use: FLYA13 (RRID:CVCL_8870)
Comments Group: Retrovirus packaging cell line.
Population: Caucasian.
Omics: SNP array analysis.
Derived from sampling site: Acetabulum; connective tissue.
Sequence variations Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Fibrosarcoma (NCIt: C3043)
Fibrosarcoma (ORDO: Orphanet_2030)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0317 (HT-1080)
Children:
CVCL_EG37 (FLYA-JET)
Sex of cell Male
Age at sampling 35Y
Category Cancer cell line
STR profile Source(s): ECACC

Markers:
AmelogeninX,Y
CSF1PO12
D5S81811,13
D7S8209,10
D13S31712,14
D16S5399,12
TH016
TPOX8
vWA14,19

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Publications

PubMed=7494248; DOI=10.1128/JVI.69.12.7430-7436.1995
Cosset F.-L., Takeuchi Y., Battini J.-L., Weiss R.A., Collins M.K.L.
High-titer packaging cells producing recombinant retroviruses resistant to human serum.
J. Virol. 69:7430-7436(1995)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections ECACC; 95091901
Ximbio; 151655
Cell line databases/resources CLO; CLO_0003368
CLDB; cl1376
LINCS_LDP; LCL-1437
Encyclopedic resources Wikidata; Q54835019
Gene expression databases GEO; GSM827429
Polymorphism and mutation databases Progenetix; CVCL_8870
Entry history
Entry creation06-Jun-2012
Last entry update16-Dec-2021
Version number22