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Cellosaurus GSU (CVCL_8877)

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Cell line name GSU
Accession CVCL_8877
Resource Identification Initiative To cite this cell line use: GSU (RRID:CVCL_8877)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations Heterozygous for KRAS p.Gly12Asp (c.35G>A) (CCLE).
Heterozygous for TP53 p.Val272Met (c.814G>A) (CCLE).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.31
Native American0.03
East Asian, North77.2
East Asian, South22.13
South Asian0
European, North0.34
European, South0
Disease Gastric carcinoma (NCIt: C4911)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 37Y
Category Cancer cell line
STR profile Source(s): RCB

Markers:
AmelogeninX
CSF1PO9,12
D5S8189,12
D7S8208,12
D13S31712
D16S53911
TH017,9
TPOX10,11
vWA14,16

Run an STR similarity search on this cell line
Publications

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections RCB; RCB2278
Cell line databases/resources CCLE; GSU_STOMACH
Cell_Model_Passport; SIDM01551
DepMap; ACH-000485
Ontologies CLO; CLO_0050794
Biological sample resources BioSample; SAMN03471948
BioSample; SAMN10987761
Chemistry resources PharmacoDB; GSU_416_2019
Gene expression databases ArrayExpress; E-MTAB-2770
GEO; GSM887030
GEO; GSM888100
Other Wikidata; Q54871783
Polymorphism and mutation databases IARC_TP53; 28289
LiGeA; CCLE_054
Entry history
Entry creation06-Jun-2012
Last entry updated06-Sep-2019
Version number14