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Cellosaurus U937(CD59-) (CVCL_8932)

[Text version]

Cell line name U937(CD59-)
Synonyms CD59- U937
Accession CVCL_8932
Resource Identification Initiative To cite this cell line use: U937(CD59-) (RRID:CVCL_8932)
Comments Derived from sampling site: Pleural effusion.
Sequence variations PICALM-MLLT10 (CALM-AF10) gene fusion (from parent cell line).
Hemizygous for PTEN p.Gly129fs*51 (c.387_388insCGCC) (from parent cell line).
Homozygous for TP53 c.559+1G>A (p.Val173Trpfs*59); splice donor mutation (from parent cell line).
Disease Adult acute monocytic leukemia (NCIt: C8263)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0007 (U-937)
Sex of cell Male
Age at sampling 37Y
Category Cancer cell line
Publications

PubMed=7518799
van den Berg C.W., Williams O.M., Morgan B.P.
Presence of a dysfunctional form of CD59 on a CD59+ subclone of the U937 cell line.
Immunology 81:637-642(1994)

Cross-references
Other Wikidata; Q54973789
Entry history
Entry creation06-Jun-2012
Last entry update02-Jul-2020
Version number9