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Cellosaurus DT40-ITRP1(-/-)-ITPR2(-/-) (CVCL_8B31)

[Text version]
Cell line name DT40-ITRP1(-/-)-ITPR2(-/-)
Synonyms IP3R type1^(-)/2^(-) DT40
Accession CVCL_8B31
Resource Identification Initiative To cite this cell line use: DT40-ITRP1(-/-)-ITPR2(-/-) (RRID:CVCL_8B31)
Comments Group: Bird cell line.
Knockout cell: Method=Targeted integration; UniProtKB; A0A8V0ZEC6; ITPR1.
Knockout cell: Method=Targeted integration; UniProtKB; F1P1X4; ITPR2.
Transformant: NCBI_TaxID; 11864; Avian leukosis virus (ALV).
Cell type: B-cell; CL=CL_0000236.
Disease Chicken bursal lymphoma (NCIt: C134556)
Species of origin Gallus gallus (Chicken) (NCBI Taxonomy: 9031)
Breed/subspecies: Hy-Line SC.
Hierarchy Parent: CVCL_0249 (DT40)
Sex of cell Female
Age at sampling 1D
Category Cancer cell line
Publications

PubMed=9214625; DOI=10.1093/emboj/16.11.3078
Sugawara H., Kurosaki M., Takata M., Kurosaki T.
Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1,4,5-trisphosphate receptors in signal transduction through the B-cell antigen receptor.
EMBO J. 16:3078-3088(1997)

Cross-references
Cell line collections (Providers) RCB; RCB1717
Cell line databases/resources CLO; CLO_0051501
Encyclopedic resources Wikidata; Q54831487
Entry history
Entry creation23-Feb-2016
Last entry update30-Jan-2024
Version number10