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Cellosaurus GENEA002 (CVCL_9011)

Cell line name GENEA002
Synonyms Genea002; SIVF002; SIVF-02; SIVF02
Accession CVCL_9011
Resource Identification Initiative To cite this cell line use: GENEA002 (RRID:CVCL_9011)
Comments From: Genea Biocells, Ltd; Sydney; Australia.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-12-0151.
Registration: Swiss research registry; BAG-hES-IMP-0026.
Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC14-38.
Omics: Array-based CGH.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Donor information: Embryo is sibling to that giving rise to GENEA048 (Cellosaurus=CVCL_9057).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=27345802

Markers:
AmelogeninX,Y
CSF1PO10,11
D2S133823
D3S135814,17
D5S81811,12
D7S8208,10
D8S117912,14
D13S31711
D16S53911,12
D18S5113,16
D19S43313,14
D21S1128,30
FGA19,21
TH016
TPOX8
vWA14,16

Run an STR similarity search on this cell line
Web pages https://web.archive.org/web/20180912205435/http://geneabiocells.com/services/shelf-products/human-embryonic-stem-cells/
Publications

PubMed=20198447; DOI=10.1007/s11626-010-9298-y
Bradley C.K., Chami O., Peura T.T., Bosman A.G., Dumevska B., Schmidt U., Stojanov T.
Derivation of three new human embryonic stem cell lines.
In Vitro Cell. Dev. Biol. Anim. 46:294-299(2010)

PubMed=20428235; DOI=10.1371/journal.pone.0010263
Hovatta O., Jaconi Devaud M.E.E., Tohonen V., Sloan-Bena F., Gimelli S., Bosman A.G., Holm F., Wyder S., Zdobnov E.M., Irion O., Andrews P.W., Antonarakis S.E., Zucchelli M., Kere J., Feki A.
A teratocarcinoma-like human embryonic stem cell (hESC) line and four hESC lines reveal potentially oncogenic genomic changes.
PLoS ONE 5:E10263-E10263(2010)

PubMed=25316320; DOI=10.1021/pr500649m
McQuade L.R., Balachandran A., Scott H.A., Khaira S., Baker M.S., Schmidt U.
Proteomics of Huntington's disease-affected human embryonic stem cells reveals an evolving pathology involving mitochondrial dysfunction and metabolic disturbances.
J. Proteome Res. 13:5648-5659(2014)

PubMed=27217344; DOI=10.5966/sctm.2015-0224
Caron L., Kher D., Lee K.L., McKernan R., Dumevska B., Hidalgo A., Li J., Yang H., Main H., Ferri G., Petek L.M., Poellinger L., Miller D.G., Gabellini D., Schmidt U.
A human pluripotent stem cell model of facioscapulohumeral muscular dystrophy-affected skeletal muscles.
Stem Cells Transl. Med. 5:1145-1161(2016)

PubMed=27345802; DOI=10.1016/j.scr.2015.10.002
Dumevska B., Bosman A.G., McKernan R., Goel D., Peura T.T., Schmidt U.
Derivation of Genea002 human embryonic stem cell line.
Stem Cell Res. 16:155-158(2016)

PubMed=28445466; DOI=10.1038/nature22312
Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C., Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G., Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A., Eggan K.C.
Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations.
Nature 545:229-233(2017)

Cross-references
Cell line databases/resources ISCR; 1163
NIHhESC; NIHhESC-12-0151
Encyclopedic resources Wikidata; Q54835563
Entry history
Entry creation06-Jun-2012
Last entry update30-Jan-2024
Version number19