Cellosaurus cell line COST (CVCL_9491)

• Gene fusion; HGNC; 427; ALK + HGNC; 7910; NPM1; Name(s)=NPM1-ALK (PubMed=15356659; PubMed=26657151).
  

PubMed=15356658; DOI=10.1038/sj.leu.2403465
Drexler H.G., MacLeod R.A.F.
Malignant hematopoietic cell lines: in vitro models for the study of anaplastic large-cell lymphoma.
Leukemia 18:1569-1571(2004)

PubMed=15356659; DOI=10.1038/sj.leu.2403464
Lamant L., Espinos E., Duplantier M., Dastugue N., Robert A., Allouche M., Ragab J., Brousset P., Villalva C., Gascoyne R.D., Al Saati T., Delsol G.
Establishment of a novel anaplastic large-cell lymphoma-cell line (COST) from a 'small-cell variant' of ALCL.
Leukemia 18:1693-1698(2004)

PubMed=16596703; DOI=10.1002/pmic.200500647
Cussac D., Pichereaux C., Colomba A., Capilla F., Pont F., Gaits-Iacovoni F., Lamant L., Espinos E., Burlet-Schiltz O., Monsarrat B., Delsol G., Payrastre B.
Proteomic analysis of anaplastic lymphoma cell lines: identification of potential tumour markers.
Proteomics 6:3210-3222(2006)

PubMed=26657151; DOI=10.1038/onc.2015.456
Ceccon M., Merlo M.E.B., Mologni L., Poggio T., Varesio L.M., Menotti M., Bombelli S., Rigolio R., Manazza A.D., Di Giacomo F., Ambrogio C., Giudici G., Casati C., Mastini C., Compagno M., Turner S.D., Gambacorti-Passerini C., Chiarle R., Voena C.
Excess of NPM-ALK oncogenic signaling promotes cellular apoptosis and drug dependency.
Oncogene 35:3854-3865(2016)