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Cellosaurus SN12C-PM6 (CVCL_9549)

Cell line name SN12C-PM6
Synonyms SN12CPM6; SN12-PM6; SN12PM6; PM6; LM1
Accession CVCL_9549
Resource Identification Initiative To cite this cell line use: SN12C-PM6 (RRID:CVCL_9549)
Comments Omics: CNV analysis.
Omics: Transcriptome analysis.
Sequence variations Homozygous for TP53 p.Glu336Ter (c.1006G>T) (from parent cell line).
Disease Renal cell carcinoma (NCIt: C9385)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1705 (SN12C)
CVCL_DG80 (SN12C-PM6-2)
Sex of cell Male
Age at sampling 43Y
Category Cancer cell line

PubMed=2706827; DOI=10.1007/BF01753659
Naito S., Walker S.M., Fidler I.J.
In vivo selection of human renal cell carcinoma cells with high metastatic potential in nude mice.
Clin. Exp. Metastasis 7:381-389(1989)

Singh R.K., Bucana C.D., Gutman M., Fan D., Wilson M.R., Fidler I.J.
Organ site-dependent expression of basic fibroblast growth factor in human renal cell carcinoma cells.
Am. J. Pathol. 145:365-374(1994)

Yano S., Shinohara H., Herbst R.S., Kuniyasu H., Bucana C.D., Ellis L.M., Davis D.W., McConkey D.J., Fidler I.J.
Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis.
Cancer Res. 60:4959-4967(2000)

PubMed=20952505; DOI=10.1158/0008-5472.CAN-10-2279
Lopez-Lago M.A., Thodima V.J., Guttapalli A., Chan T., Heguy A., Molina A.M., Reuter V.E., Motzer R.J., Chaganti R.S.K.
Genomic deregulation during metastasis of renal cell carcinoma implements a myofibroblast-like program of gene expression.
Cancer Res. 70:9682-9692(2010)

Cell line collections KCLB; 80026
Gene expression databases GEO; GSM374474
GEO; GSM579206
GEO; GSM579401
Other Wikidata; Q54955020