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Cellosaurus PC-3M (CVCL_9555)

[Text version]
Cell line name PC-3M
Synonyms PC3-M; PC-3/M; PC3M; Pc3M
Accession CVCL_9555
Resource Identification Initiative To cite this cell line use: PC-3M (RRID:CVCL_9555)
Comments Population: Caucasian.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Children:
CVCL_5J43 (hVEGF-luc/PC3M)CVCL_6E87 (PC-3/MA2)CVCL_G257 (PC-3M-1E8)
CVCL_G256 (PC-3M-2B4)CVCL_L155 (PC-3M-LN1)CVCL_D577 (PC-3M-luc-C6)
CVCL_5J25 (PC-3M-luc2)CVCL_L158 (PC-3M-Pro1)CVCL_5J10 (PC-3M-Red-FLuc)
CVCL_4885 (PC3-MM2)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): KCLB

Markers:
AmelogeninX
CSF1PO11
D3S135816
D5S81813
D7S8208,11
D13S31711
FGA24
TH016,7
TPOX8,9
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=447482
Kaighn M.E., Narayan K.S., Ohnuki Y., Lechner J.F., Jones L.W.
Establishment and characterization of a human prostatic carcinoma cell line (PC-3).
Invest. Urol. 17:16-23(1979)

PubMed=7471073
Ohnuki Y., Marnell M.M., Babcock M.S., Lechner J.F., Kaighn M.E.
Chromosomal analysis of human prostatic adenocarcinoma cell lines.
Cancer Res. 40:524-534(1980)

PubMed=7017212; DOI=10.1093/jnci/66.6.1003
Pollack M.S., Heagney S.D., Livingston P.O., Fogh J.
HLA-A, B, C and DR alloantigen expression on forty-six cultured human tumor cell lines.
J. Natl. Cancer Inst. 66:1003-1012(1981)

PubMed=3335022
Alley M.C., Scudiero D.A., Monks A., Hursey M.L., Czerwinski M.J., Fine D.L., Abbott B.J., Mayo J.G., Shoemaker R.H., Boyd M.R.
Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay.
Cancer Res. 48:589-601(1988)

Cross-references
Cell line collections (Providers) CLS; 305061
KCLB; 80020
NCI-DTP; PC-3/M
Cell line databases/resources cancercelllines; CVCL_9555
TOKU-E; 3851
Anatomy/cell type resources BTO; BTO:0005220
Chemistry resources ChEMBL-Cells; CHEMBL4295486
ChEMBL-Targets; CHEMBL4296484
PubChem_Cell_line; CVCL_9555
Encyclopedic resources Wikidata; Q54938435
Gene expression databases GEO; GSM1178559
GEO; GSM1178560
GEO; GSM1178561
Polymorphism and mutation databases Cosmic; 1945877
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number25