ID   PC-3M
AC   CVCL_9555
SY   PC3-M; PC-3/M; PC3M; Pc3M
DR   BTO; BTO:0005220
DR   cancercelllines; CVCL_9555
DR   ChEMBL-Cells; CHEMBL4295486
DR   ChEMBL-Targets; CHEMBL4296484
DR   CLS; 305061
DR   Cosmic; 1945877
DR   GEO; GSM1178559
DR   GEO; GSM1178560
DR   GEO; GSM1178561
DR   KCLB; 80020
DR   NCI-DTP; PC-3/M
DR   PubChem_Cell_line; CVCL_9555
DR   TOKU-E; 3851
DR   Wikidata; Q54938435
RX   PubMed=447482;
RX   PubMed=3335022;
RX   PubMed=7017212;
RX   PubMed=7471073;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
ST   Source(s): KCLB
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 11
ST   D3S1358: 16
ST   D5S818: 13
ST   D7S820: 8,11
ST   FGA: 24
ST   TH01: 6,7
ST   TPOX: 8,9
ST   vWA: 17
DI   NCIt; C4863; Prostate carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0035 ! PC-3
SX   Male
AG   62Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 05-10-23; Version: 25
//
RX   PubMed=447482;
RA   Kaighn M.E., Narayan K.S., Ohnuki Y., Lechner J.F., Jones L.W.;
RT   "Establishment and characterization of a human prostatic carcinoma
RT   cell line (PC-3).";
RL   Invest. Urol. 17:16-23(1979).
//
RX   PubMed=3335022;
RA   Alley M.C., Scudiero D.A., Monks A., Hursey M.L., Czerwinski M.J.,
RA   Fine D.L., Abbott B.J., Mayo J.G., Shoemaker R.H., Boyd M.R.;
RT   "Feasibility of drug screening with panels of human tumor cell lines
RT   using a microculture tetrazolium assay.";
RL   Cancer Res. 48:589-601(1988).
//
RX   PubMed=7017212; DOI=10.1093/jnci/66.6.1003;
RA   Pollack M.S., Heagney S.D., Livingston P.O., Fogh J.;
RT   "HLA-A, B, C and DR alloantigen expression on forty-six cultured human
RT   tumor cell lines.";
RL   J. Natl. Cancer Inst. 66:1003-1012(1981).
//
RX   PubMed=7471073;
RA   Ohnuki Y., Marnell M.M., Babcock M.S., Lechner J.F., Kaighn M.E.;
RT   "Chromosomal analysis of human prostatic adenocarcinoma cell lines.";
RL   Cancer Res. 40:524-534(1980).
//