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Cellosaurus SLK (CVCL_9569)

[Text version]

Cell line name SLK
Synonyms KS-SLK
Accession CVCL_9569
Resource Identification Initiative To cite this cell line use: SLK (RRID:CVCL_9569)
Comments Problematic cell line: Contaminated. Shown to be a Caki-1 derivative (PubMed=22987579). Originally thought to originate from a 28 year old male patient with HIV-1 negative Kaposi sarcoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00477.
Population: Caucasian.
Doubling time: 24-36 hours (PubMed=7520247).
Sequence variations Mutation; HGNC; 9884; RB1; Simple; p.Leu98Pro (c.293T>C); Zygosity=Heterozygous (from parent cell line).
Disease Clear cell renal cell carcinoma (NCIt: C4033)
Clear cell renal carcinoma (ORDO: Orphanet_319276)
Derived from metastatic site: Skin.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0234 (Caki-1)
Sex of cell Male
Age at sampling 49Y
Category Cancer cell line
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations_v11_distribution.xlsx

PubMed=7520247; DOI=10.1097/00002030-199405000-00002
Herndier B.G., Werner A., Arnstein P., Abbey N.W., Demartis F., Cohen R.L., Shuman M.A., Levy J.A.
Characterization of a human Kaposi's sarcoma cell line that induces angiogenic tumors in animals.
AIDS 8:575-581(1994)

Boshoff C.
Kaposi's sarcoma.
(In) Human cell culture. Vol. 2. Cancer Cell Lines part 2; Masters J.R.W., Palsson B.O. (eds.); pp.157-166; Kluwer Academic Publishers; New York (1999)

PubMed=22987579; DOI=10.1002/ijc.27849
Sturzl M., Gaus D., Dirks W.G., Ganem D., Jochmann R.
Kaposi's sarcoma-derived cell line SLK is not of endothelial origin, but is a contaminant from a known renal carcinoma cell line.
Int. J. Cancer 132:1954-1958(2013)

Cell line collections HIVReagentProgram; ARP-9402
Cell line databases/resources SKY/M-FISH/CGH; 3862
Biological sample resources BioSample; SAMN03151616
Other Wikidata; Q54954867
Entry history
Entry creation06-Jun-2012
Last entry update23-Sep-2021
Version number19